arXiv:2605.18740v4 Announce Type: replace
Abstract: Multimodal Large Language Models (MLLMs) still struggle with fine-grained visual understanding, where answers often depend on small but decisive evidence in the full image. We observe a regional-to-global perception gap: the same MLLM answers fine-grained questions more accurately when conditioned on evidence-centered crops than on the corresponding full images, suggesting that many failures stem from difficulty to focus on relevant evidence rather than insufficient local recognition ability. Motivated by this observation, we propose Vision-OPD (Vision On-Policy Distillation), a regional-to-global self-distillation framework that transfers the model's own privileged regional perception to its full-image policy. Vision-OPD instantiates two conditional policies from the same MLLM: a crop-conditioned teacher and a full-image-conditioned student. The student generates on-policy rollouts, and Vision-OPD minimizes token-level divergence between the teacher and student next-token distributions along these rollouts. This enables the model to internalize the benefit of visual zooming without external teacher models, ground-truth labels, reward verifiers, or inference-time tool use. Experiments on multiple fine-grained visual understanding benchmarks show that Vision-OPD models achieve competitive or superior performance against much larger open-source, closed-source, and "Thinking-with-Images" agentic models. The code is available at https://github.com/VisionOPD/Vision-OPD
Science Journals
arXiv:2605.19262v2 Announce Type: replace
Abstract: Masked diffusion language models (MDLMs) are emerging as a compelling new paradigm for text generation, but their training-time security remains largely unexplored. Existing backdoor attacks on Gaussian diffusion models or autoregressive language models do not directly apply to MDLMs because MDLMs rely on discrete state corruption and iterative denoising rather than continuous noising or left-to-right prediction. In this work, we present the first systematic study of training-time backdoor attacks on MDLMs. We propose SHADOWMASK, a backdoor attack that modifies the MDLM forward corruption process by replacing the standard all-mask terminal distribution with a trigger-mask mixture prior. This creates a dedicated denoising pathway from trigger-corrupted states to attacker-specified targets while preserving clean denoising behavior. We further provide a principled mathematical formulation by defining the backdoored forward process, deriving the reverse-time posterior, and obtaining the continuous-time training objective. Evaluations on DiT-based MDLM and LLaDA-8B-Instruct across WikiText-103, OpenWebText, and Alpaca show that SHADOWMASK achieves near-100% attack success, substantially outperforms standard data poisoning, largely preserves clean utility, remains effective under full-model and parameter-efficient fine-tuning, and is robust against representative defenses.
arXiv:2605.19320v2 Announce Type: replace
Abstract: Faithful text rendering remains a persistent weakness of large text-to-image generative models, as it requires both semantic instruction following and fine-grained glyph-level structure. Prior methods often improve this ability through architecture-specific modules or encoder modifications, which complicate deployment across foundation models. We study text rendering as a post-training preference-alignment problem and propose TextAlign, a non-invasive framework that keeps the generator architecture unchanged. The key component is a hierarchical vision-language model (VLM)-based reward that decomposes rendering errors into global, word, and glyph levels, then converts binary defect judgments into a scalar preference signal. The resulting signal supports both Group Relative Policy Optimization (GRPO) and Direct Preference Optimization (DPO). Experiments on FLUX.1-dev and Z-Image-Turbo show consistent gains in OCR-based text accuracy without degrading general generation quality. Compared with strong foundation and text-rendering baselines, including SD3.5, Qwen-Image, AnyText, and TextDiffuser, these results indicate that reward design offers a scalable alternative to model redesign for improving text rendering.
arXiv:2605.19805v2 Announce Type: replace
Abstract: Irregular multivariate time series impose a trade-off for long-horizon forecasting: discrete methods can distort temporal structure via re-gridding, while continuous-time models often require sequential solvers prone to drift. To bridge this gap, we present Latent Laplace Diffusion (LLapDiff), a generative framework that models the target as a low-dimensional latent trajectory, enabling horizon-wide generation without step-by-step integration over physical time. We guide the reverse process utilizing a stable modal parameterization motivated by stochastic port-Hamiltonian dynamics, and parameterize its mean evolution in the Laplace domain via learnable complex-conjugate poles, enabling direct evaluation over irregular timestamps. We also link continuous dynamics to irregular observations through renewal-averaging analysis, which maps sampling gaps to effective event-domain poles and motivates a gap-aware history summarizer. Extensive experiments show that LLapDiff improves over baselines in long-horizon forecasting, and its continuous-time generative nature supports missing-value imputation by querying the same model at historical timestamps. Code is available at https://github.com/pixelhero98/LLapDiffusion.
arXiv:2605.19860v2 Announce Type: replace
Abstract: We extend the CCSDTQ implementation in CFOUR to UHF and ROHF references and demonstrate its efficiency. We apply it to basis set convergence of post-CCSDT(Q) corrections for the W4-08 thermochemical dataset. Convergence of (Q)$_\Lambda$--(Q) is relatively rapid. For difficult species (e.g., B2, O3), CCSDTQ--CCSDT(Q)$_\Lambda$ may converge more slowly than (5)$_\Lambda$, but the effects and and basis-set trends oppose each other. Consequently, a single-shot CCCSDTQ(5)$_\Lambda$-CCSDT(Q)$_\Lambda$ correction appears most efficient. For radicals with bifurcating UHF solutions, energetics of the `less spin-contaminated' solution are clearly more well-behaved. Our best computed adiabatic electron affinity of ozone is in excellent agreement with experiment.
arXiv:2605.20306v2 Announce Type: replace
Abstract: We introduce WildRoadBench, a wild aerial road-damage grounding benchmark that couples direct visual grounding by vision-language models with autonomous research-and-engineering by LLM-driven agents on a single professionally annotated UAV corpus. The same image set and the same per-class AP_50 metric are evaluated under two protocols. The VLM Track measures whether a fixed VLM can localise domain-specific damage from one image and one short prompt under a unified prompting, decoding and parsing pipeline. The Agent Track measures whether an autonomous agent, given only a written task brief, a small exploratory slice and a fixed interaction budget, can search the public web, adapt pretrained components, write training and inference code, and submit predictions through a scalar-feedback oracle on a hidden holdout. We benchmark a broad pool of closed-source frontier models and open-source VLMs together with several frontier LLM-driven agents. Both routes remain far from reliable performance in this wild setting: closed-source frontier models lead the VLM leaderboard but still leave more than half of the metric on the table; open-source grounders plateau well below them, and newer generations or reasoning-style variants do not consistently improve grounding; small targets collapse for every open-source model; agents lag the strongest VLM despite richer affordances, and several fail to land a valid submission within the budget. We release the code and data at https://anonymous.4open.science/r/wildroadbench-0607 to support reproducible follow-up research.
arXiv:2605.20402v3 Announce Type: replace
Abstract: MXFP4 arithmetic can dramatically accelerate reinforcement learning (RL) post-training of large language models (LLMs), yet the quantization error introduces severe accuracy degradation. Existing work treats the quantization error as a monolithic noise term, missing the distinct mechanisms upon interpreting how quantization error damages training. We prove an exact three-way decomposition of quantization error and show how each component dominates a distinct RL training pathway. Our theoretical and empirical analysis decomposes the MXFP4 quantization error into three additive components: "scale bias" from power-of-two rounding, "deadzone truncation" from zeroing small values, and "grid noise" from rounding to the nearest 4-bit grid. Each component dominates a distinct RL failure mode: scale bias accumulates multiplicatively through the backward pass, affecting gradient accuracy; deadzone truncation degrades rollout quality; and grid noise raises the policy's entropy. We combine corrections that are RL failure mode-targeted but not component-exclusive: Macro-block scaling to reduce scale bias, Outlier Fallback recovers deadzone entries, but also partially reduces scale bias induced error, and Adaptive Quantization Noise (AQN) for controlling the policy entropy. On Qwen2.5-3B dense and Qwen3-30B-A3B-Base mixture-of-experts model, the targeted corrections recover BF16 accuracy to within 0.7% and exceed BF16 by +1.0% respectively.
arXiv:2605.31381v2 Announce Type: replace
Abstract: We evaluate the consistency of automated judges in conducting a multi-dimensional safety evaluation in a reference-free setup. Our results indicate that Large Language Models are unreliable judges in identifying safety issues related to machine-generated advice in regulated domains such as finance, although they are more reliable at identifying more overt forms of unsafe/harmful content such as violence. The degree of inconsistency in a model's judgments can vary significantly by the chosen safety criteria and can be impacted by the language of the content and its linguistic style as well. Finally, there is high disagreement among different judges for the same output, across domains, safety criteria, and languages. These findings provide new insights on the practice of using LLMs as evaluators and offer several recommendations for practitioners on how to use automated judges in practical scenarios.
arXiv:2606.03471v1 Announce Type: new
Abstract: This paper proposes, for the first time, a rigorous formal definition of the concept of Machine Theory of Mind, based on principles supported by evidence from cognitive psychology, neuroscience and artificial intelligence, and uses the above as a lens to examine state-of-the-art and current efforts in the field, driving a potential agenda for further research there able to "crack" the problem. It also advances a general holistic meta-model for Machine Theory of Mind, and examines the state of the art when it comes to empirically benchmarking such models.
arXiv:2604.15097v2 Announce Type: replace
Abstract: This beta technical report asks how reusable experience should be represented so that it can function as effective test-time control and as a substrate for iterative evolution. We study this question in 4.590 controlled trials across 45 scientific code-solving scenarios. We find that documentation-oriented Skill packages provide unstable control: their useful signal is sparse, and expanding a compact experience object into a fuller documentation package often fails to help and can degrade the overall average. We further show that representation itself is a first-order factor. A compact Gene representation yields the strongest overall average, remains competitive under substantial structural perturbations, and outperforms matched-budget Skill fragments, while reattaching documentation-oriented material usually weakens rather than improves it. Beyond one-shot control, we show that Gene is also a better carrier for iterative experience accumulation: attached failure history is more effective in Gene than in Skill or freeform text, editable structure matters beyond content alone, and failure information is most useful when distilled into compact warnings rather than naively appended. On CritPt, gene-evolved systems improve over their paired base models from 9.1% to 18.57% and from 17.7% to 27.14%. These results suggest that the core problem in experience reuse is not how to supply more experience, but how to encode experience as a compact, control-oriented, evolution-ready object.
arXiv:2606.00918v2 Announce Type: replace
Abstract: We present a novel, practical attack on the IPv6 Fragment ID generation algorithm of XNU, which is the kernel used by Apple products such as macOS and iOS. This attack exploits a race-condition vulnerability in the algorithm's pseudorandom number generator (PRNG) to cryptanalytically break, learn the internal state of the generator, and consequently predict fragment IDs, which, in turn, facilitates an IPv6 fragment spoofing attack. As far as we know, this is the first cryptanalytic attack that is based on exploiting race-conditions. With fragment spoofing, it is possible to partially manipulate UDP datagrams and TCP segments. We showcase a new type of attack on NFS (UDP) where an off-path attacker modifies a file as it is written, and an attack on HTTP (TCP) where an off-path attacker modifies an HTTP request. Apple assigned this vulnerability the CVE identifier CVE-2024-27823 and patched all its XNU-based products against the attack.
arXiv:2606.01162v2 Announce Type: replace
Abstract: Workflow scheduling in cloud computing demands the intelligent allocation of dynamically arriving, graph-structured workflows with varying deadlines onto ever-changing virtual machine resources. However, existing deep reinforcement learning (DRL) schedulers remain limited by rigid, single-path inference architectures that struggle to handle diverse scheduling scenarios. We introduce $\textbf{DEFT}$ ($\textbf{D}$eadline-p$\textbf{E}$rceptive Mixture-o$\textbf{F}$-Exper$\textbf{t}$s), an innovative DRL policy architecture that leverages a specialized mixture of experts, each trained to manage different levels of deadline tightness. To our knowledge, DEFT is the first to introduce and validate a Mixture-of-Experts architecture for dynamic cloud workflow scheduling. By adaptively routing decisions through the most appropriate experts, DEFT is capable of meeting a broad spectrum of deadline requirements that no single expert can achieve. Central to DEFT is a $\textbf{graph-adaptive}$ gating mechanism that encodes workflow DAGs, task states, and VM conditions, using cross-attention to guide expert activation in a fine-grained, deadline-sensitive manner. Experiments on dynamic cloud workflow benchmarks demonstrate that DEFT significantly reduces execution cost and deadline violations, outperforming multiple state-of-the-art DRL baselines.
arXiv:2606.01166v2 Announce Type: replace
Abstract: Computer-use agents extend language models from text generation to sustained interaction with files, terminals, browsers, and external tools. This shift creates safety risks that are difficult to detect from isolated prompts or final responses, because harm often emerges only through multi-step execution traces whose individual actions appear locally benign. We introduce BraveGuard, a self-evolving defense framework for training guard models from open-world threat signals and realistic agent trajectories. BraveGuard mines recent research sources to identify emerging risks and attack patterns, instantiates them as executable computer-use tasks, collects agent rollouts, and derives trajectory-level supervision for guard model training. As new threats and validation failures appear, the pipeline can be repeated, yielding an adaptive defense loop rather than a static, benchmark-driven training process. We instantiate BraveGuard by training multiple guard backbones, including Qwen3-Guard and Llama-Guard variants, and evaluate the resulting guards on trajectory-level agent-safety benchmarks. BraveGuard consistently improves safety detection across computer-use trajectories. On AgentHazard, it substantially improves detection accuracy over off-the-shelf guard models, with accuracy increasing from 38.79% to 82.38% under the averaged guard-model setting. These results show that guard supervision grounded in open-world threat discovery and realistic agent execution can improve safety monitoring beyond fixed taxonomies and synthetic prompt-level data. BraveGuard offers a scalable path toward adaptive defenses for computer-use agents facing evolving real-world risks.
arXiv:2604.15713v3 Announce Type: replace
Abstract: Type annotations are essential when printing terms in a way that preserves their meaning under reparsing and type inference. We study the problem of complete and minimal type annotations for rank-one polymorphic $\lambda$-calculus terms, as used in Isabelle. Building on prior work by Smolka, Blanchette et al., we give a metatheoretical account of the problem, with a full formal specification and proofs, and formalize it in Isabelle/HOL. Our development is a series of experiments featuring human-driven and AI-driven formalization workflows: a human and an LLM-powered AI agent independently produce pen-and-paper proofs, and the AI agent autoformalizes both in Isabelle, with further human-hinted AI interventions refining and generalizing the development.
arXiv:2606.01532v2 Announce Type: replace
Abstract: Positional encoding (PE) is widely viewed as necessary for transformers to process ordered sequences: without them, the next-token map appears permutation-invariant in its context tokens. This intuition underlies all prior universality results, which rely on positional information to prove that transformers with chain-of-thought can perform arbitrary computation, i.e., they are Turing complete. We revisit this belief in the regime most relevant to long-form reasoning, where generation proceeds through a finite sliding context window. Our opening perception is that the window mechanism itself (mildly) breaks the permutation symmetry. To distill and precisely capture the degree of this added expressiveness, we introduce an abstract autoregressive model, the HIST model, in which each update depends only on constant-size internal state and the token-count histogram within the current window. We prove that this HIST model is Turing complete by showing that the evolution of the window can reveal the token that has just left the window, which suffices to simulate Turing-complete Post machines. We then construct a sliding-window transformer over a constant-size token alphabet, without PE, and show that it can simulate the HIST model. Our result demonstrates that positional encodings are not indispensable for transformers to perform universal computation: The window sliding itself already breaks permutation symmetry and captures sufficient positional information.
arXiv:2606.02091v2 Announce Type: replace
Abstract: Block diffusion speculative decoding accelerates LLM inference by predicting all tokens within a block simultaneously for the target model to verify in parallel. Predicting an entire block at once requires a sufficiently capable draft model and effective utilization of the target model's internal knowledge. However, the state-of-the-art method DFlash constrains all draft layers to share a single fused representation derived from only a few target layers, limiting per-layer expressiveness and hindering further scaling of draft capacity. In this paper, we present \modelname, which flares out the narrow conditioning bottleneck of DFlash through a lightweight layer-wise fusion mechanism: each draft layer attends to its own learnable combination of a broad set of target layers at negligible overhead, simultaneously injecting richer target knowledge and providing every draft layer with a distinct input. This enhanced per-layer expressiveness enables scaling the draft model to deeper architectures with consistent gains. We further scale training data from 800K to 2.4M samples to fully exploit the enlarged capacity. On six benchmarks spanning mathematical reasoning, code generation, and conversation, \modelname attains average wall-clock speedups of 5.52x on Qwen3-4B, 5.46x on Qwen3-8B, and 3.91x on GPT-OSS-20B, improving over DFlash by roughly 11\%, 8\%, and 5\% respectively. Our code is available at https://github.com/Tencent/AngelSlim.
arXiv:2606.02132v2 Announce Type: replace
Abstract: Agentic reinforcement learning can induce tool abuse, where models overuse external tools even for queries solvable by internal reasoning. Existing approaches mitigate this issue with uniform tool-use penalties or hard limits, which reduce tool frequency but may also suppress useful tool-assisted exploration. We propose EAPO, an Efficient Agentic Policy Optimization framework that learns selective tool use. EAPO introduces tool-free trajectories into each rollout group, applies difficulty-aware reward shaping to penalize redundant tool calls mainly on easier queries, and uses confidence-aware token reweighting to improve policy learning. Across nine mathematical and knowledge-intensive reasoning benchmarks, EAPO consistently improves the accuracy efficiency trade-off on Qwen2.5-3B, Qwen2.5-7B, and Llama3.1-8B. Compared with GRPO, EAPO improves average performance by 10.45%, 7.27%, and 9.69%, while reducing average tool calls by 18.33%, 18.33%, and 24.59%, respectively. These results show that agents can learn when not to use tools without compromising tool-integrated reasoning.
arXiv:2606.02437v2 Announce Type: replace
Abstract: Parameter-efficient fine-tuning (PEFT) is usually treated as a cheaper alternative to full fine-tuning. We study a broader role: small trainable adapters as persistent local state on top of strong shared foundation models. In this framing, the base model provides shared competence while adapters carry instance-specific behavior such as preferences, skills, tool habits, and memory-like updates. We organize the problem around three scaling axes: Scale Up, where stronger shared priors make small local updates more useful; Scale Down, where we study how small adapters can be while remaining reliable; and Scale Out, where many persistent adapted instances coexist. MinT provides one infrastructure example for managing adapter identity, revision, provenance, evaluation, and serving residency. Together, the results suggest that PEFT can be a compact substrate for persistent personal models rather than only a budget substitute for full fine-tuning.
arXiv:2604.16808v4 Announce Type: replace
Abstract: Existing lip-sync deepfake detectors rely on pixel artifacts or audio-visual correspondence, and both fail under generator or language shift because the features they learn are tied to the training distribution. We take a different approach. Authentic lip motion is constrained by tissue mechanics and neuromuscular bandwidth; current generators typically do not impose these constraints, producing trajectories with elevated variance in velocity, acceleration, and jerk that real speech does not exhibit. We exploit this signal, which we term temporal lip jitter, by computing kinematic statistics from 64 perioral landmarks over short sliding windows and feeding them into a lightweight three-branch network. The model uses only landmark coordinates: no pixels, no audio, and no voiceprint data. We train only on English data and test in a zero-shot setting on five unseen generators and seven languages.
arXiv:2604.01960v3 Announce Type: replace
Abstract: Although Approximate Nearest Neighbor (ANN) search has been extensively studied, large-k ANN queries that aim to retrieve a large number of nearest neighbors remain underexplored, despite their numerous real-world applications. Existing ANN methods face significant performance degradation for such queries. In this work, we first investigate the reasons for the performance degradation of quantization-based ANN indexes: (1) the inefficiency of existing top-k collectors, which incurs significant overhead in candidate maintenance, and (2) the reduced pruning effectiveness of quantization methods, which leads to a costly re-ranking process. To address this, we propose a novel bucket-based result collector (BBC) to enhance the efficiency of existing quantization-based ANN indexes for large-k ANN queries. BBC introduces two key components: (1) a bucket-based result buffer that organizes candidates into buckets by their distances to the query. This design reduces ranking costs and improves cache efficiency, enabling high performance maintenance of a candidate superset and a lightweight final selection of top-k results. (2) two re-ranking algorithms tailored for different types of quantization methods, which accelerate their re-ranking process by reducing either the number of candidate objects to be re-ranked or cache misses. Extensive experiments on real-world datasets demonstrate that BBC accelerates existing quantization-based ANN methods by up to 3.8x at recall@k = 0.95 for large-k ANN queries.
arXiv:2604.04439v2 Announce Type: replace
Abstract: We study how different visual information sources contribute to human decision making in dynamic visual environments. Using Atari-HEAD, a large-scale Atari gameplay dataset with synchronized eye-tracking, we introduce a controlled ablation framework as a means to reverse-engineer the contribution of peripheral visual information, explicit gaze information in the form of gaze maps, and past-state information from human behavior. We train action-prediction networks under six settings that selectively include or exclude these information sources. Across 20 games, peripheral information shows by far the strongest contribution, with median prediction-accuracy drops in the range of 35.27-43.90% when removed. Gaze information yields smaller drops of 2.11-2.76%, while past-state information shows a broader range of 1.52-15.51%, with the upper end likely more informative due to reduced peripheral-information leakage. To complement aggregate accuracies, we cluster states by true-action probabilities assigned by the different model configurations. This analysis identifies coarse behavioral regimes, including focus-dominated, periphery-dominated, and more contextual decision situations. These results suggest that human decision making in Atari depends strongly on information beyond the current focus of gaze, while the proposed framework provides a way to estimate such information-source contributions from behavior.
arXiv:2606.03655v1 Announce Type: new
Abstract: Recent work in defeasible reasoning has seen notions of preferential semantics and entailment in the style of Kraus et al. applied to modal logics. However, work in this field has focussed primarily on satisfiability checking, and monotonic notions of entailment, which may be inferentially weak. One particular modal logic where this has been introduced is propositional standpoint logics, where modalities can express the views of different viewpoints. This has resulted in the formalisation of propositional defeasible standpoint logic (PDSL). In this paper, we propose a means of lifting the class of (non-monotonic) rational entailment relations from traditional KLM-style reasoning to a fragment of PDSL. In order to do so, we extend the expressivity of PDSL via situated standpoint conditionals, allowing us to talk about a defeasible conditional holding in the context of a given standpoint. This allows us to re-characterise the syntax of PDSL in terms of situated conditionals, and shows that a large fragment of PDSL is expressible as a set of situated conditionals. We then focus on characterising non-monotonic entailment in this fragment, defining a method to transport any ranking-based entailment relation from the propositional case into the PDSL case. This is first described in the general case and then considered in the specific cases of rational and lexicographic closures, providing a faithful translation of each inference into PDSL. We also show that entailment-checking in this fragment of PDSL can be done largely using algorithms from the propositional case, while preserving complexity bounds.
arXiv:2604.24374v2 Announce Type: replace
Abstract: Representation learning is fundamental to NLP, but building embeddings that work well at different computational budgets is challenging. Matryoshka Representation Learning (MRL) offers a flexible inference paradigm through nested embeddings; however, learning such structures requires explicit coordination of how information is arranged across embedding dimensionality and model depth. In this work, we propose MIPIC (Matryoshka Representation Learning via Self-Distilled Intra-Relational Alignment and Progressive Information Chaining), a unified training framework designed to produce structurally coherent and semantically compact Matryoshka representations. MIPIC promotes cross-dimensional structural consistency through Self-Distilled Intra-Relational Alignment (SIA), which aligns token-level geometric and attention-driven relations between full and truncated representations using top-k CKA self-distillation. Complementarily, it enables depth-wise semantic consolidation via Progressive Information Chaining (PIC), a scaffolded alignment strategy that incrementally transfers mature task semantics from deeper layers into earlier layers. Extensive experiments on STS, NLI, and classification benchmarks (spanning models from TinyBERT to BGEM3, Qwen3) demonstrate that MIPIC yields Matryoshka representations that are highly competitive across all capacities, with significant performance advantages observed under extreme low-dimensional.
arXiv:2606.03572v1 Announce Type: new
Abstract: Deep learning has become a prevailing paradigm across a wide range of geophysical applications. Yet most existing studies concentrate on methodological refinements -- novel network architectures, physics-informed constraints, or taskspecific loss functions -- while paying comparatively little attention to a more fundamental challenge of any data-driven approach: the availability and representativeness of high-quality training data. This limitation is especially pronounced in geophysics. Unlike computer vision, which benefits from large-scale, well-curated benchmarks such as ImageNet, comparably abundant and reliably labelled geophysical data are prohibitively expensive to acquire and, in most field settings, lack accessible ground-truth supervision. To alleviate this data deficiency, we propose GeoVolDiff, a generative framework for three-dimensional geological volumes. It comprises three coupled stages: (i) constructing a foundational training corpus through physics-based forward simulation; (ii) training a Latent Diffusion Model (LDM) to capture the statistical distribution of 3D geological structures; and (iii) synthesizing diverse, structurally plausible volumes at scale for downstream geophysical tasks. We examine the utility of the synthesized data on a representative downstream task, seismic impedance inversion. Without incorporating any additional physical or geological prior, inversion networks pre-trained exclusively on synthesized data attain competitive performance on both synthetic and field datasets, indicating that data synthesised by the generative model can serve as an effective surrogate for costly field-acquired labels.
arXiv:2605.24253v3 Announce Type: replace
Abstract: Digital pathology archives increasingly contain multiple whole-slide images (WSIs) per case, capturing spatially distinct tumor regions and reflecting intrinsic morphological heterogeneity. However, most existing approaches rely on a single pathologist-selected slide, thereby discarding potentially informative evidence distributed across the remaining WSIs. To date, no autonomous framework has been proposed for comprehensive multi-WSI case processing. Here, we present an unsupervised framework for case-level analysis that integrates information from all available slides within a case. Rather than relying on a single designated slide, the proposed approach constructs case-level representations by selectively distilling informative patches across WSIs. We introduce Clustering-Based Redundancy-Reduced Instance Sampling for Pathology (CRISP), a two-stage framework that first reduces redundancy within individual WSIs and subsequently applies clustering-based sampling to select a compact yet representative set of patches for the entire case. The resulting patch set captures case-level heterogeneity while avoiding exhaustive processing of gigapixel images, and directly serves as a retrieval index. Using two Mayo Clinic breast cancer datasets for diagnosis and treatment planning, we demonstrate that CRISP consistently matches or surpasses the current standard practice of combined model and pathologist slide selection for patient/case search and retrieval. By automating case-level processing and eliminating subjective WSI selection, CRISP potentially enables the exploitation of clinically relevant information distributed across multiple WSIs that is currently overlooked.