arXiv:2606.09641v1 Announce Type: new Abstract: The dominant paradigm in video retrieval relies on embedding-based full-corpus scanning, which suffers from inherent computational inefficiency and the semantic asymmetry between information-dense videos and sparse textual queries. To bridge this gap, we introduce \textbf{MAVIS}, a novel multi-agent framework that rethinks retrieval as cooperative reasoning rather than brute-force search. MAVIS first bridges the granularity mismatch by parsing raw videos into a \textbf{Structured Semantic Library}, enabling explicit attribute-level indexing. During retrieval, a planner decomposes complex user intents into atomic sub-tasks, dispatching specialized agents to independently nominate candidates. Crucially, MAVIS employs a \textbf{Logic-aware Debate} mechanism with a strict veto protocol, where agents collaboratively prune logical mismatches to identify a compact set of ``controversial'' candidates for fine-grained verification. This agentic workflow effectively bypasses the inefficiency of full-library traversal. Extensive experiments on MSR-VTT, MSVD, and ActivityNet demonstrate that MAVIS achieves competitive performance without task-specific fine-tuning, offering a scalable and interpretable alternative to traditional dual-encoder approaches.
Science Journals
arXiv:2606.09653v1 Announce Type: new Abstract: Learned representations across models and modalities often exhibit striking structural similarities, suggesting shared underlying concept decompositions. However, concept alignment remains poorly defined: existing approaches optimize different objectives under the same terminology, obscuring what is actually aligned. We propose a unifying framework that decomposes alignment along two axes: what is aligned (representations vs. concepts) and at what level (instance-wise vs. distributional). This induces four corresponding properties -- instance-wise and distributional variants of translation and concept consistency -- and reveals precisely which of these guarantees existing methods provide. We further introduce \InterVenchA, an intervention-based benchmark that separately measures extraction quality, translation quality, and concept consistency. Through theory and experiments, we show that commonly assumed equivalences between alignment objectives fail in practice: optimizing one property does not reliably recover the others, and purely unsupervised objectives fail to recover meaningful instance-level alignment. We then propose the Coupled Sparse Autoencoder (CoSAE), which jointly enforces complementary alignment objectives. Strong alignment emerges only in this regime. Surprisingly, as little as 0.1\% paired data is sufficient to recover instance-level alignment when anchoring distributional objectives. Overall, our results show that concept alignment is fundamentally multi-objective: it must be defined, measured, and optimized as such.
arXiv:2606.09655v1 Announce Type: new Abstract: Despite remarkable progress in machine translation (MT), non-AI communities have raised growing concerns about MT systems, suggesting a noticeable gap between technical advancement and the needs of real-world users. For instance, while NLP researchers focus on benchmark performance, end users care about ethical concerns, trust, reliability, costs, and more. We argue that listening to various user communities is essential so that research efforts would be directed towards the problems that the communities care about. To this end, we present a large-scale analysis, for the first time, that investigates what four stakeholder communities (AI developers, professional translators, language learners, and language service providers) post about MT technology on social media. To do so, we construct a dataset of 79,286 posts and comments from Reddit, Facebook, Bluesky, and Mastodon from 2019 to 2025, and analyse where these communities disagree, and how and why. Overall, we find that communities often disagree, and even show strong conflicts due to polarised sentiments on topics such as translation quality, efficiency, and reliability. This is because these communities approach these topics differently: the AI community frames them as technical and computational problems, while non-AI (user) communities care more about quality nuances, time savings, user trust, and broader social issues.
arXiv:2606.09658v1 Announce Type: new Abstract: Muon has recently emerged as a state-of-the-art optimizer for pretraining Large Language Models (LLMs) and vision classifiers. Despite its efficiency advantage over Adam and SGD, the feature-learning advantage of Muon remains unclear. This paper investigates Muon's feature-learning advantage through the lens of robustness and transferability. First, by evaluating pretrained models on corrupted images and texts, we show that features learned by Muon are consistently more robust than those learned by Adam and SGD across different architectures, including transformers and Convolutional Neural Networks (CNNs). Using trained layer-wise probes, we further show that this robustness advantage is reflected in larger logit margins across layers. Second, by training linear classifiers or fine-tuning full models from pretrained parameters on downstream tasks, we demonstrate that Muon-learned features transfer more effectively than those learned by Adam and SGD. This transferability advantage is further supported by the diversity of hidden states across layers, as measured by effective rank. Finally, in a representative classification problem with multi-component features, we prove that Muon attains larger margins and higher effective rank than Adam and SGD, providing theoretical support for our empirical findings.
arXiv:2606.09659v1 Announce Type: new Abstract: Long-context language model inference is bottlenecked by memory, as the KV cache grows with context length. Recent techniques to compress the KV cache fall short: they either degrade model quality substantially or require considerable time and compute to compress a single long prompt. Furthermore, many methods require the input to fit within the target model's context window, and are generally incompatible with modern production inference engines. Encoder-decoder compressors, which map a long token sequence to a shorter sequence of latent embeddings consumed by a decoder, are an appealing alternative in principle. However, existing approaches are not competitive with KV cache compression on the accuracy-efficiency frontier. In this work, we revisit encoder-decoder compression and close this gap. We first perform an architecture search, pre-training many variants from scratch to determine how best to design and train encoder-decoder compressors. Guided by our findings, we continually pre-train a family of 0.6B-encoder, 4B-decoder models on over 350B tokens each, at compression ratios of 1:4, 1:8, and 1:16. We introduce Latent Context Language Models (LCLMs), a family of compressors that improve the Pareto frontier across general-task performance, compression speed, and peak memory usage. We demonstrate that LCLMs serve as efficient backbones for long-horizon agents, letting the agent skim through a compressed long context and adaptively expand relevant segments on demand.
arXiv:2606.09661v1 Announce Type: new Abstract: Purpose: Up to 4% of adults will develop strabismus in their lifetime. The most common surgical intervention involves adjusting the length of one or more extraocular muscles to correct the angular deviation. This correction depends on surgical expertise and statistical reference tables, which often fail to yield optimal results for patients with atypical eye morphology. Our work proposes a physics-based modeling approach to personalized surgical planning, accounting for patient-specific eye anatomy. Methods: We built a physics-based simulator of the eye and its muscles, incorporating patient-specific geometry and Hill-type muscle biomechanics. We solve an optimization problem to find the surgical dosage that minimizes angular deviation. The model is implemented as a fully differentiable simulation, enabling efficient optimization. We validated the framework by comparing its predictions with standard surgical tables for emmetropic eyes before applying it to anatomically atypical virtual patients. Results: Our model's predictions for emmetropic eyes were first validated, demonstrating a strong fit with standard surgical tables. More importantly, for high-myopia models, the framework computed a clinically significant increase in the required surgical dosage compared to standard eyes. This computed recession difference is highly relevant as surgical plans are adjusted in 0.5 mm increments. Conclusion: Our results show that our model provides a calibrated surgical plan that, unlike standard tables, also accounts for pathologies involving atypical eye shapes. This patient-specific model represents a step toward personalized surgical planning, with the potential to improve dosage accuracy and surgical outcomes for atypical cases.
arXiv:2606.09676v1 Announce Type: new Abstract: Boundary layers provide a demanding test for numerical solvers because the solution may remain almost constant over most of the domain while changing rapidly in a narrow region near the boundary. This paper studies a singularly perturbed one-dimensional transport boundary-value problem with increasing Peclet number $(\mathrm{Pe})$. A local Legendre wavelet collocation method (LWM) is compared with a standard soft-boundary physics-informed neural network (PINN) for this benchmark. The wavelet approximation uses locally supported Legendre polynomial basis functions and converts the problem into a square algebraic collocation system with residual, boundary, and interface-continuity equations. Numerical experiments are performed for $\mathrm{Pe}=1,10,100,$ and $1000$. The LWM captures all four cases, with the largest error remaining below $5\times 10^{-3}$. The standard soft-boundary PINN performs well for the mild cases but fails to resolve the sharp boundary layer for the larger Peclet numbers. The results show that local wavelet collocation is more reliable than the standard soft-boundary PINN for this benchmark, while dense near-boundary evaluation helps reveal errors that may be missed on coarse grids.
arXiv:2606.09679v1 Announce Type: new Abstract: We describe our system for the SoccerNet 2026 Player-Centric Ball-Action Spotting Challenge, which requires predicting who performs which action and when, across eight classes in broadcast soccer. Building on the three FOOTPASS baselines [1] (TAAD, TAAD+GNN, and TAAD+DST), we contribute four extensions: (1) gradient check pointing to enable full-backbone fine-tuning on a single GPU; (2) fusion of GNN logits into the DST encoder, combining graph-based tactical context with per-player visual features; (3) square-root frequency class weighting to address the 213:1 pass-to-tackle imbalance in the training data; and (4) a post processing pipeline comprising per-class logit gating, temporal frame refinement, jersey re-assignment, and a two-model ensemble. Our system achieves 0.548 Macro F1 on the test set and 0.446 on the challenge set (server evaluation).
Quality-Diversity Search in Sound Generation: Investigating Innovation Engines for Audio Exploration
arXiv:2606.09780v1 Announce Type: new Abstract: This study addresses the challenges composers and sound designers face in creating and refining tools to achieve their musical goals. Using evolutionary processes to promote diversity and foster serendipitous discoveries, we automate the search through uncharted sonic spaces for sound discovery, arguing that diversity-promoting algorithms can bridge the gap between the theoretical realisation and practical accessibility of sounds. We describe a system for generative sound synthesis combining Quality Diversity (QD) algorithms with a supervised discriminative model, inspired by the Innovation Engine algorithm, and explore different configurations and the interplay between the chosen synthesis approach and the discriminative model. We examine the interaction between Compositional Pattern Producing Networks (CPPNs) and Digital Signal Processing (DSP) graphs, introducing a novel approach that uses multiple specialised CPPNs for different frequency ranges; this yields simpler networks while maintaining performance comparable to single-CPPN setups. We also investigate evolutionary stepping stones by analysing goal switches between musical and non-musical contexts, revealing how lineages traverse unlikely paths to current elites. Expanding the behaviour space of a previous study to include various sound durations, we uncover specialisation within temporal niches. Results indicate that CPPN and DSP graphs coupled with a Multi-dimensional Archive of Phenotypic Elites (MAP-Elites) and a deep learning classifier can generate a substantial variety of synthetic sounds, diverse and innovative across temporal and contextual dimensions. We present the generated sound objects through an online explorer and as rendered sound files, and, in the context of music composition, an experimental application that showcases their creative potential across various durations and contexts.
arXiv:2606.09788v1 Announce Type: new Abstract: Large-scale document processing requires contextually aware table extraction (TE) that is both accurate and efficient. Yet current approaches require billions of parameters, hundreds of autoregressive steps, or costly API inference. Motivated by this, we introduce the Page-Object Table Transformer (POTATR), a lightweight 29M parameter image-to-graph model that extends the Table Transformer (TATR) for contextualized page-level TE. POTATR outperforms all models tested on the PubTables-v2 Single Pages benchmark -- including frontier MLLMs -- achieving $\textrm{GriTS}_\textrm{Con}$ of 0.964 while running over 130$\times$ faster at roughly 300$\times$ lower cost. Further, POTATR's output is spatially grounded: every recognized element has a bounding box, enabling visual verification and geometric text assignment. As a result, POTATR performs unified page-level TE while composing with other models, enabling extension to scanned documents via external OCR and to full-document TE via techniques like cross-page merging. Code and models will be released.
arXiv:2602.14033v1 Announce Type: cross Abstract: Future sixth-generation (6G) mobile networks will demand artificial intelligence (AI) agents that are not only autonomous and efficient, but also capable of real-time adaptation in dynamic environments and transparent in their decisionmaking. However, prevailing agentic AI approaches in networking, exhibit significant shortcomings in this regard. Conventional deep reinforcement learning (DRL)-based agents lack explainability and often suffer from brittle adaptation, including catastrophic forgetting of past knowledge under non-stationary conditions. In this paper, we propose an alternative solution for these challenges: Bayesian reasoning via Active Inference (BRAIN) agent. BRAIN harnesses a deep generative model of the network environment and minimizes variational free energy to unify perception and action in a single closed-loop paradigm. We implement BRAIN as O-RAN eXtended application (xApp) on GPU-accelerated testbed and demonstrate its advantages over standard DRL baselines. In our experiments, BRAIN exhibits (i) robust causal reasoning for dynamic radio resource allocation, maintaining slice-specific quality of service (QoS) targets (throughput, latency, reliability) under varying traffic loads, (ii) superior adaptability with up to 28.3% higher robustness to sudden traffic shifts versus benchmarks (achieved without any retraining), and (iii) real-time interpretability of its decisions through human-interpretable belief state diagnostics.
arXiv:2606.07655v1 Announce Type: cross Abstract: The ubiquity of social media platforms facilitates malicious linguistic steganography, posing significant security risks. However, detection is severely hampered by two fundamental issues during model training. Firstly, extreme class imbalance (less than 1% steganographic samples) induces a strong decision bias. Secondly, the invisibility of generative steganography means its features are nearly indistinguishable from benign text; this similarity, compounded by their extreme rarity, leads to severe feature marginalization, where faint steganographic signals are completely overwhelmed. To directly address these optimization-level challenges, we propose FADRW (Feature-Aware Modulated and Dynamically Reweighted Loss), a novel loss function framework engineered for few-shot steganalysis. FADRW employs Dynamic Reweighting to progressively counteract decision bias, and a Feature-Aware Modulation module to structurally reshape the feature space, preventing feature marginalization by enhancing the separability of these subtle features. Extensive experiments on datasets from three real-world social platforms demonstrate that FADRW significantly outperforms state-of-the-art methods, particularly in the challenging few-shot steganographic sample scenario.
arXiv:2606.07914v1 Announce Type: cross Abstract: We study component recovery and mixing-matrix estimation from unlabeled finite mixtures whose observable distributions share the same latent components but have unknown mixing weights. The main identifying signal is marginal independence: each component is assumed to be independent on at least one coordinate pair, but no labels, clean component samples, or mixing weights are observed. We first prove a structural result for product components: under linear independence of the univariate marginals, any independent affine combination of the components must coincide with a single component. We then extend this principle to observable mixtures and show that, under full-rank and no-cancellation conditions, marginally independent affine combinations recover the corresponding latent components. When every component is independent on some coordinate pair, all components are identifiable, and the mixing matrix is recoverable under the stated completion conditions. Finally, we propose a Product-Marginal Maximum Mean Discrepancy (PM-MMD) estimator over affine combinations of the observable mixtures and prove uniform convergence and stability under approximate marginal independence. This framework also separates the empirical roles of the assumptions: irreducibility is, in general, not directly testable from the unlabeled mixtures alone, whereas marginal independence yields a candidate-level diagnostic through held-out PM-MMD. Controlled and flow-cytometry experiments show when marginal independence provides a useful recovery signal. In the reported multi-component comparisons, condition-aware representative selection stabilizes PM-MMD and improves recovery relative to clustering, factorization, and pairwise mixture-proportion baselines using the same unlabeled mixtures.
arXiv:2606.07921v1 Announce Type: cross Abstract: Weyl fermions in inversion-symmetric Weyl semimetals occur in pairs of opposite chirality, leading to symmetric optical responses under circularly-polarised light and a vanishing net photocurrent. Here, we show that tailored two-colour light fields break this symmetry and enable selective excitation of individual Weyl nodes. The interference between a circularly-polarised $\omega$ field and a phase-locked linearly-polarised $2\omega$ field generates a chirality-dependent redistribution of carriers in momentum space, resulting in a nonzero controllable photocurrent. We demonstrate that both the magnitude and sign of the photocurrent can be tuned via the relative phase and field strength of the two colours, and identify an optimal regime in which chiral selectivity is maximised. Our results establish a general route to optically-controlled chiral charge dynamics in Weyl semimetals using polarisation-structured light.
arXiv:2606.08202v1 Announce Type: cross Abstract: Most statistical and machine learning methods for directed interactions focus on pairwise effects among variables. Even existing cyclic models represent feedback primarily through node-level dependencies, making large-scale recurrent organization difficult to estimate and compare. This limitation is particularly acute in biological and neural systems, where interactions are highly recurrent and involve many overlapping cycles. We introduce a variational framework for statistical inference on cyclic interactions. Directed interactions are represented as edge flows on a simplicial complex and evolved under an energy-minimizing dynamical system. The resulting dynamics separate transient interaction components from persistent harmonic flows, yielding a low-dimensional cycle space that captures stable recurrent organization. Rather than enumerating individual cycles, the proposed framework represents cyclic interactions as elements of a Hilbert space, enabling projection, averaging, comparison, and population-level statistical inference. We establish theoretical properties of the harmonic projection, including characterization of the cycle space, variance reduction, and population inference. Simulations demonstrate substantially improved recovery of cyclic structure in dense recurrent systems compared with existing directed-interaction methods. Applied to resting-state fMRI from 400 human subjects, the framework reveals reproducible large-scale cyclic organization that is not detectable through edgewise averaging. These results provide a scalable statistical framework for studying recurrent interactions in high-dimensional dynamical systems.
arXiv:2606.08227v1 Announce Type: cross Abstract: A well-known model in game theory, the Volunteer's Dilemma describes a group of $n$ players who decide whether to volunteer for a collective benefit at a personal cost, or to abstain and risk forfeiting the benefit altogether. A quantum version of this dilemma, developed within the Eisert-Wilkens-Lewenstein framework, allows each player to manipulate one qubit of a shared entangled state, leading to symmetric Nash equilibria with higher expected payoffs than in the classical game. Existing analyses, however, assume maximal entanglement. Within the same framework, we introduce a generalized Quantum Volunteer's Dilemma with a tunable entanglement parameter $\gamma$ and study the extent to which equilibrium behavior depends on the level of entanglement. We derive explicit conditions relating $\gamma$, the number of players, and the players' strategies under which symmetric Nash equilibria exist, focusing on two canonical strategy profiles: one for $2\leq n\leq 9$, and one for even $n$. We find that maximal entanglement is not required to sustain symmetric equilibria. Instead, equilibrium behavior persists above a threshold value, which we compute analytically in both cases. We also demonstrate that the threshold value directly depends on system size. This characterization is directly relevant for implementations on resource-constrained quantum devices, where entanglement is inherently limited.
arXiv:2606.08247v1 Announce Type: cross Abstract: Acute asthma risk assessment requires rapid interpretation of respiratory sounds, oxygenation, airflow limitation, speech ability, work of breathing, mental status, and response to reliever therapy. Conventional audio-only classifiers can detect wheeze-like patterns but often lack transparent clinical reasoning and safe escalation logic. This paper presents AeroSpectra Sentinel, a client-side research prototype and decision-support workflow that combines short-time Fourier transform (STFT) respiratory sound analysis, lightweight machine-learning screening, clinical feature fusion, and a five-stage large language model (LLM) prompt-chaining process. The workflow separates signal acquisition, preprocessing, acoustic feature extraction, ML screening, clinical guardrails, and FHIR-ready reporting. We evaluated the audio screening component on a public respiratory sound dataset containing 1,211 WAV recordings from five labels. Using a stratified subset of 584 recordings, a random forest achieved 91.10% binary accuracy and 78.69% F1-score for asthma-vs-non-asthma screening, while a feature-based multilayer perceptron achieved 89.73% accuracy and 78.26% F1-score. A compact log-spectrogram CNN achieved 73.29% accuracy and 55.17% F1-score. Multiclass classification achieved 77.40% accuracy and 77.23% macro-F1. To evaluate the LLM workflow, we conducted a scenario-based audit on 40 simulated clinical vignettes comparing one-shot prompting, prompt chaining, prompt chaining with guardrails, and prompt chaining with guardrails plus FHIR schema validation. The guardrail-plus-schema variant achieved the strongest simulated safety and documentation consistency. AeroSpectra Sentinel is intended as a research prototype, not as a diagnostic medical device or clinically validated risk-assessment product.
arXiv:2606.08370v1 Announce Type: cross Abstract: Standard dynamic vision sensors approximate retinal processing by detecting temporal contrast changes, offering high speed and high dynamic range. In this work, we explore whether incorporating additional biologically inspired processing stages - specifically spatial filtering and gain control - can offer advantages for certain downstream tasks such as saliency prediction. We present the first implementation of a multi-stage Silicon Retina model on the SCAMP-5 Pixel Processor Array, along with a GPU-based simulation framework. We evaluate the performance of our model on Video Intensity Reconstruction and Video Saliency Prediction. While the bio-inspired model is less effective at reconstructing absolute intensity frames, it achieves a 13\% reduction in saliency prediction loss in comparison to standard DVS event representation, while reducing the event rate by approximately 47\%. These experiments are obtained using a lightweight $\approx 100$k-parameter FireNet-style network, adapted from event-based reconstruction to saliency prediction. These results suggest that the silicon retina's "information distillation" mechanism can achieve a more efficient representation for downstream neural networks, particularly in bandwidth-constrained edge applications.
arXiv:2606.08437v1 Announce Type: cross Abstract: Palmprint modality offers a privacy-preserving biometric solution, yet its deployment is hindered by the domain gap between controlled enrollment and unconstrained authentication. Existing datasets are largely restricted to controlled setups and fail to capture the compound variability of real-world environments. In this paper, we introduce X-Palm, a cross-domain dataset comprising 6,006 palm images from 103 individuals (206 hands). To the best of our knowledge, X-Palm is the first palmprint dataset providing novel paired-identity acquisition specifically designed to bridge the gap between reliably controlled multispectral enrollment and unconstrained mobile authentication while encompassing a broad spectrum of in-the-wild variability. Unlike existing datasets that focus on single to a few variations, X-Palm addresses the massive modality and environmental shifts encountered in practical deployments by capturing paired data for identities across two distinct domains: (1) a controlled Multispectral Palmprint setting using our custom-developed scanner, and (2) an unconstrained smartphone palmprint setting that is participant-driven, incorporating simultaneous variations in hardware, hand pose, illumination, background, camera-to-hand distance, perspective, and palm surface conditions (e.g., moisture and occlusions). Our extensive benchmarks of 12 SOTA models reveal that while existing methods achieve high performance on controlled data, they experience severe performance collapse on X-Palm. Conversely, models trained on X-Palm demonstrate consistent robustness across domains, positioning X-Palm as a valuable resource for training a model towards real-world, cross-domain generalization. Data access instructions and the related benchmarking codes are publicly available at: https://github.com/X-Palm/X-Palm-2026
arXiv:2606.08587v1 Announce Type: cross Abstract: Statistical post-processing has proven to be an effective tool in improving ensemble forecast of different weather variables. Case studies show that post-processing can remedy the typically underdispersive and potentially biased behaviour of the ensemble while optimizing a proper scoring rule expressing the forecast skill. The price of these positive effects is generally a deterioration in sharpness; the width of the central prediction intervals and the uncertainty of the predictions are increasing, especially for shorter lead times. This work aims to reduce the extent of the latter phenomenon for neural network-based parametric post-processing methods by extending the network's loss function with a penalty term. We demonstrate the effect of the proposed technique for 2m temperature ensemble forecasts of the European Centre for Medium-Range Weather Forecasts downloaded from the EUPPBench benchmark dataset and verified against synoptic observations. Here, the predictive distribution is Gaussian, and we use the continuous ranked probability score (CRPS) as loss function. The case studies confirm a substantial relative decrease ($8.2\%-12.5\%$) in the width of the nominal central prediction interval compared to the width of the predictive distribution computed without the penalty term, while there is no deterioration in the mean CRPS of probabilistic forecasts and in the RMSE of the predictive mean.
arXiv:2606.08679v1 Announce Type: cross Abstract: Pretrained models are often evaluated on multi-task leaderboards to measure their applicability in diverse contexts. However, current methods for aggregating performance across tasks into leaderboard-level rankings do not address the uncertainty and variability at the task level. While recent works have proposed interval-based model rankings, the principled aggregation of uncertainty from individual tasks to leaderboard-level rankings remains unaddressed, and variation in models' performance across tasks is frequently obscured. In this work, we introduce a hierarchical framework that constructs model rank intervals with statistical guarantees at both levels: task-level rank confidence intervals from pairwise comparisons, and leaderboard-level rank prediction intervals using a conformal approach. This enables reliable quantification of model rank for each observed task and for new potential tasks. Experiments on simulated data and the TabArena and PromptEval (MMLU) benchmarks show that our method yields statistically valid and informative intervals, enabling reliable, uncertainty-aware model ranking on leaderboards.
arXiv:2606.09040v1 Announce Type: cross Abstract: Living organisms, from bacteria to humans, are more likely to survive if their traits enhance fitness. In populations well adapted to their environmental niches, natural selection proceeds via rarely beneficial mutations. But when a catastrophe wipes out niche diversity, sudden adaptation often follows. Here, we present a data-validated theory of natural selection in the wake of catastrophe and unveil a simple law that emerges during recovery: the mean fitness relaxes inversely with time, with a prefactor proportional to the number of traits coupled to the post-catastrophe environment. We put our approach to test using experimental fitness landscapes measured following antibiotic administration to E. coli. The resulting mean trait adaptation is not described by gradient ascent on a fitness landscape, instead it follows an algorithm known as Levenberg-Marquardt optimization. Near fitness peaks, evolutionary trajectories are biased against greediness - from an optimization perspective, post-catastrophic selection is optimistic.
arXiv:2606.09048v1 Announce Type: cross Abstract: Removing intermediate representations and separately trained decoding stages has become an important direction in generative modeling. In text-to-speech, however, high-quality systems are still commonly built through an intermediate acoustic representation before waveform synthesis. In this work, we present BareWave, a fully waveform-native framework for direct text-to-wave generation in flow-matching TTS. We consider this setting to raise three training challenges: raw-waveform modeling lacks a strong pretrained representational scaffold, different stages of training benefit from different noise schedules, and data-space perceptual objectives do not automatically share the temporal structure of the velocity-space flow objective. As a result, direct waveform training is hard to optimize efficiently, hard to push toward a strong final operating point with a fixed recipe, and hard to integrate effective perceptual refinement. Guided by this view, we develop a direct text-to-wave training framework that combines training-time representation alignment, staged noise scheduling, and velocity-aware perceptual alignment (VAPA), while preserving a single waveform-native inference path without pretrained components at test time. Experiments on zero-shot voice cloning show that strong intelligibility, speaker similarity, and naturalness can be achieved under a fully waveform-native inference path, supporting waveform-native flow-matching TTS as a practical direction. Project page with audio demos is available at https://barewave.github.io/.
arXiv:2606.09597v1 Announce Type: cross Abstract: Here we present ARTGEL, an actively regulated-temperature gel electrophoresis platform designed for long-duration experiments under independently controlled thermal and electrical conditions. ARTGEL combines thermoelectric regulation of the gel temperature, a large heated and circulated buffer reservoir, and an automated electrode-wiping mechanism that stabilizes the voltage across the gel during runs exceeding 24 h. The platform was developed to address a limitation of conventional electrophoretic mobility shift assays, which are commonly used to analyze reversible biomolecular association but usually aim to suppress reaction during electrophoresis by dilution, competitors, or reduced temperature so that the gel reports a pre-equilibrated bulk solution. For temperature-sensitive systems, these strategies can alter the chemical state during loading and migration and obscure whether the measured band pattern reflects the original bulk sample or a re-equilibrated state inside the porous gel. Rather than attempting to quench reactions, ARTGEL enables electrophoresis to be performed at the same temperature as complementary bulk measurements, so that reversible association can be quantified directly in the gel and compared with matched measurements in solution. Using DNA origami assemblies, we show that ARTGEL preserves distinct temperature-dependent association states, resolves reaction-dependent distortions of migrating bands, and supports extraction of in-gel kinetic and thermodynamic parameters from reaction-diffusion-advection modeling.
arXiv:2606.09636v1 Announce Type: cross Abstract: Double microwave shielding employs $\sigma^{+}$- and $\pi$-polarized microwave fields, tuned close to the lowest rotational transition, to engineer a long-range repulsive barrier between polar molecules. By preventing molecules from reaching the short range, this technique suppresses detrimental two-body losses and recently enabled the realization of molecular Bose-Einstein condensates and self-bound droplets. Yet, the optimal operating regimes of the shielding mechanism remain largely unexplored. Here, by leveraging the underlying universality of the scattering problem, we systematically map the four-dimensional microwave parameter space-spanned by the detunings and intensities of the two fields-to identify configurations that maximize both shielding efficiency and interaction tunability. We define optimal operating regimes as configurations that are strictly free of field-linked bound states while sufficiently suppressing two-body losses to exceed typical lifetimes of ultracold samples. In these regimes, we evaluate the elastic-to-inelastic collision ratios required for efficient evaporative cooling and explore the accessible tuning range of the effective dipolar interactions. Finally, to identify the best platforms for future quantum simulation experiments, we conduct a global survey of candidate molecular species under realistic field constraints. We identify heavy, strongly dipolar molecules as the most promising candidates, demonstrating that they can achieve extreme loss suppression alongside robust interaction tunability using only moderate field strengths.