arXiv:2606.08147v1 Announce Type: cross Abstract: DNA cis-regulatory elements (CREs) such as enhancers control gene expression levels. Accurately predicting regulatory activity from DNA sequences is valuable but challenging, as it requires understanding complex biological regulatory processes. Existing methods typically regress activity scores from sequences in a black-box manner, limiting both interpretability and regression performance. Meanwhile, large language models (LLMs) benefit from explicit reasoning processes, yet directly applying LLMs to raw DNA sequences performs poorly. In this paper, we bridge this gap by introducing R3LM, a framework that teaches LLMs reasoning-informed regression on regulatory DNA through structured biological knowledge. Specifically, we design a biologically grounded data format that structures DNA's regulatory information for improved LLM understanding, and construct CRE-ReasonBench, the first dataset that associates DNA sequences and activity scores with mechanistic reasoning traces. Through two-stage training that first teaches LLMs reasoning over structured biological information then performs regression, R3LM achieves state-of-the-art performance on enhancer prediction across three cell types, outperforming both LLMs with raw sequence input and specialized DNA models while providing interpretable mechanistic explanations. We expect R3LM as an interpretable reward model that can effectively assist biologists in CRE design. Code is available at https://github.com/DuanYi516/R3LM.
Science Journals
arXiv:2606.08331v1 Announce Type: new Abstract: Plasmas in space and astrophysical environments are frequently found in (quasi-)stationary states not in thermal equilibrium, indicated by velocity distribution functions (VDFs) featuring nonthermal characteristics, such as Lorentzian high-energy tails and kinetic (temperature and strahl/beam) anisotropies. For decades, in-situ observations of electrons and ions in the solar corona, solar wind or planetary magnetospheres have been modelled using so-called Kappa VDFs, whose standard form, however - depending on the considered VDF moment - imposes stringent constraints on the minimum value of the Kappa power-law parameter. Such limitations have posed difficulties on the derivation of a fully-consistent hydrodynamic formulation of suprathermal plasmas. To improve this situation, the recently proposed regularized Kappa VDF avoids strict constraints on the Kappa parameter by introducing an exponential, regularizing cut-off. In this work we assume that the plasma particles are described by regularized-Kappa VDFs that feature anisotropies not only in their thermal velocity spread parameters but also in their exponential cut-offs. The dielectric tensor components for waves propagating along a magnetic field are derived, in terms of new plasma dispersion functions. The resulting dispersion equations are solved with two complementary techniques, namely by using the analytical expressions derived here and by employing the ALPS code. This is done for physical parameters that give rise to electromagnetic and electrostatic instabilities. Both approaches show excellent agreement and the results demonstrate how an anisotropy in the regularizing cut-off of VDFs can serve, depending on an instability's nature, either as a stabilization factor or as an additional free energy source.
arXiv:2606.08332v1 Announce Type: new Abstract: Self-supervised learning (SSL) has achieved remarkable representation learning performance, but many existing methods rely on large batch sizes, memory banks, momentum encoders, or global synchronization mechanisms that substantially increase computational cost and training complexity. In this work, we propose Semantic Mutual Information (SMI), a lightweight self-supervised objective derived from a mutual-information-inspired dependency formulation under Gaussian assumptions. Unlike conventional correlation matching objectives that operate on high-dimensional feature correlation matrices, SMI performs optimization on a sample-level dependency matrix through a nonlinear transformation of pairwise correlations. This formulation induces distinct optimization dynamics that emphasize strongly dependent semantic pairs while maintaining representation diversity. Experimental results on ImageNet using a ResNet-50 backbone demonstrate that SMI achieves competitive linear evaluation performance relative to state-of-the-art SSL approaches while substantially reducing computational complexity. Across multiple low-resource benchmarks, SMI consistently improves transfer performance over Barlow Twins, particularly on fine-grained datasets. Furthermore, analyses of optimization dynamics and representation geometry suggest improved alignment--redundancy balance, greater feature diversity, and more spatially localized semantic representations. These results indicate that nonlinear dependency optimization provides an effective and computationally efficient alternative to conventional correlation-based self-supervised learning objectives.
arXiv:2606.09099v1 Announce Type: new Abstract: Autonomous UAV swarms require scalable coordination mechanisms that maintain mission performance under limited communication, environmental uncertainty, and component failures. Centralized approaches provide global coordination but suffer from communication bottlenecks and single-node vulnerabilities, whereas fully decentralized methods often lack mission-level consistency. This paper presents Layered Autonomous Edge Intelligence (LAEI), a UAV-swarm framework that combines onboard learned policies with lightweight mission-level supervision. Each UAV performs local perception, obstacle avoidance, and action selection onboard, while the supervisory layer provides adaptive goal reassignment, fault-aware recovery, and context-dependent policy guidance without directly controlling low-level actions. LAEI further incorporates recovery strategies, including dynamic reassociation, backup supervisory support, and fallback local autonomy, to maintain mission continuity under representative failure scenarios. We evaluate LAEI in simulated UAV-swarm scenarios using mission completion time, collision rate, and coverage efficiency. The results show that LAEI reduces mission completion time and improves operational efficiency while maintaining collision-aware distributed UAV-level decision-making.
arXiv:2606.09100v1 Announce Type: new Abstract: Community detection is a fundamental problem in the analysis of complex networks. It has applications across social, biological, and financial domains. Traditional algorithms such as Louvain, LPA, and modularity optimization often require manual parameter tuning. They also suffer from inaccurate cluster center selection and struggle with scalability. To address these challenges, we propose Automatic Laplacian Centrality Means (ALCMeans), a novel community detection algorithm. ALCMeans combines Laplacian energy-based automatic center identification with DeepWalk embeddings for robust node representation. Unlike existing Laplacian-based and clustering methods, ALCMeans eliminates the need to predefine the number of communities, enhances cluster center selection using structural importance, and leverages representation learning for more accurate and stable assignments. Experimental results on benchmark datasets demonstrate 10 to 20 percent higher NMI and ARI scores compared to Louvain, Newman-Girvan, LPA, Fast-Greedy, and a recent GNN-based competitor (MAGI, KDD 2024). Additional evaluations with modularity and F1-scores confirm the superiority of ALCMeans. Ablation studies highlight the critical contributions of each component. Despite its reliance on DeepWalk parameters and increased runtime relative to lightweight heuristics, ALCMeans consistently outperforms state-of-the-art methods. This makes it a promising tool for real-world network analysis.
arXiv:2606.08345v1 Announce Type: new Abstract: Large language models (LLMs) have shown strong performance in financial analysis and surface-level factual error detection, yet their ability to identify fraudulent financial misinformation in audited corporate reporting remains underexplored. Existing financial and audit benchmarks mainly focus on factual verification, numerical reasoning, rule compliance, or audit workflows, but rarely evaluate misleading disclosure narratives or management explanations that obscure the true drivers of reported performance. We introduce AuditFraudBench, an enforcement-grounded benchmark constructed from authentic company filings and regulatory materials, including original and restated 10-K and 10-Q filings, structured financial statements, MD&A disclosures, and SEC Accounting and Auditing Enforcement Releases (AAERs). AuditFraudBench contains three tasks: Profit Source Attribution, Misleading Narrative Detection, and Fraud Pattern Classification, which evaluate whether models can identify the true source of reported performance, detect misleading disclosure framing, and classify misconduct mechanisms into known manipulation patterns. We evaluate GPT, DeepSeek, and Qwen series LLMs on the benchmark. Results show that both proprietary and open models still struggle to jointly reason over financial figures, disclosure framing, restatement evidence, and enforcement-grounded fraud mechanisms. AuditFraudBench provides a challenging testbed for audit-relevant, evidence-grounded evaluation of LLMs in financial reporting.
arXiv:2606.08346v1 Announce Type: new Abstract: Reinforcement learning with verifiable rewards (RLVR) has become a dominant paradigm for improving the reasoning capabilities of large language models (LLMs). Recent tree-based methods such as TreeRPO extend flat trajectory sampling with tree-structured rollouts to obtain dense, step-level reward signals without a separate process reward model. However, not all trees are equally informative: trees where all leaves succeed, all leaves fail, or the policy already predicts the reward distribution contribute little to gradient updates, wasting compute. We introduce CATPO (Critique-Augmented Tree Policy Optimization), which diagnoses and addresses this waste at the tree level. CATPO first scores each tree via a tree informativeness score, F(T), combining leaf-outcome diversity with policy-reward decorrelation at zero extra compute. For dead-wrong trees where all branches fail, CATPO applies critique-guided healing: it locates the shallowest failure point, generates a natural-language critique, and grafts refined continuations to recover training signal. Finally, an informativeness-weighted loss scales each tree's gradient contribution by its normalized score, concentrating parameter updates on the most informative trees while preserving overall gradient magnitude. Experiments on Qwen2.5-Math-1.5B trained with the MATH dataset show that CATPO achieves 37.5% macro accuracy across four benchmarks (AIME24, MATH-500, OlympiadBench, and MinervaMath), improving over TreeRPO by 1.9% and GRPO by 4.8%.
arXiv:2606.09104v1 Announce Type: new Abstract: Deep reinforcement learning (DRL) frameworks for portfolio optimization have shown promise for their ability to learn allocation rules dynamically from market data. However, these models fail to account for fat-tailed returns, which characterize actual market behavior with more frequent extreme events. Furthermore, historical data is treated homogeneously, without accounting for temporal importance, leading models to fail during regime changes. We propose a new BAVAR-BLED algorithm that combines methods derived from Bayesian-Averaging Vector Autoregressive (BAVAR) and the Black-Litterman model using Elliptical Distributions (BLED) within a TD3 architecture. BAVAR captures a set of vector autoregressive representations that consider multi-scale temporal features, enabling adaptive allocation decisions based on regime-aware estimates of return expectations and dispersion matrices. These estimates serve as prior inputs to BLED, a model that uses Student's t-distributions, allowing for more realistic fat tail return estimates. The BAVAR-BLED algorithm uses transformer networks for view construction and CNNs for risk-aversion estimates, which modify dynamic allocation decisions based on market conditions. An evaluation of 29 Dow Jones Industrial Average constituents over a decade-long market period shows that BAVAR-BLED significantly outperforms state-of-the-art methods, achieving Sharpe and Sortino ratios of 1.72 and 2.70, respectively, and total returns of 57.26%.
arXiv:2606.09111v1 Announce Type: new Abstract: Unmanned Aerial Vehicle (UAV) multispectral point clouds (MPC) provide high-dimensional spatial-spectral data for sub-canopy target detection; however, their efficacy is significantly compromised by severe illumination heterogeneity caused by vegetation shadows. To address this, we propose a prior-free anomaly detection framework capable of robustly handling lighting variations. First, we formulate solar angle estimation as an inverse optimization problem. By coupling spectral indices with a ray-tracing model, this strategy achieves Prior-Free Shadow Extraction without relying on flight metadata, effectively distinguishing dark objects from true shadows. Second, to mitigate spectral distortions, we introduce an Illumination-Consistent Sparse Representation mechanism. Unlike standard reconstruction methods, we construct a background dictionary strictly from neighbors sharing the same illumination state. This constraint effectively disentangles spectral reflectance from lighting variations, ensuring that targets are represented solely by physically consistent background points. Experimental results indicate that the proposed method significantly improves the separability between anomalies and background in complex forest environments, demonstrating superior performance over state-of-the-art baselines. This framework is particularly suited for identifying camouflaged military targets, mapping fallen tree trunks, and uncovering archaeological ruins hidden beneath dense foliage.
arXiv:2606.08379v1 Announce Type: new Abstract: This study addresses the optimal execution of large stock sell programs by introducing TT-DAC-PS (Twin-Target Deterministic Actor-Critic with Policy Smoothing), a deterministic actor-critic architecture that combines twin exponential-moving-average critic targets with pessimistic min backup, TD3-style target policy smoothing noise, delayed actor updates, and conservative Q regularisation to curb overestimation. Exploration uses Ornstein-Uhlenbeck (OU) noise with a hybrid schedule: deterministic episode-wise decay, variance-guided adjustment based on recent reward dispersion, and a Soft Actor-Critic (SAC)-style temperature that is learned and mapped to the noise scale. The environment integrates Almgren-Chriss (AC) trade impact with Limit Order Book (LOB) prices and volumes, normalised state features, per-step volume participation caps, and a utility-based reward. The trade execution algorithm is applied to LOB data for ten U.S. stocks. Performance is assessed against reinforcement-learning baseline algorithms, including Proximal Policy Optimisation (PPO), Soft Actor-Critic (SAC), and Advantage Actor-Critic (A2C), as well as alternative trade execution algorithms, including Time-Weighted Average Price (TWAP), Volume-Weighted Average Price (VWAP), and AC. The proposed model consistently reduces mean implementation shortfall percentage with competitive variance, outperforming classical baselines and standard reinforcement-learning benchmark models.
arXiv:2606.08380v1 Announce Type: new Abstract: Domain-specific Field Programmable Gate Array (FPGA) architectures increasingly integrate specialized hardblocks, such as Tensor Slices, to accelerate artificial intelligence and machine learning workloads. Despite their efficiency benefits, these architectures remain difficult to program because designers typically rely on manual Register-Transfer Level (RTL) integration to access these hardblocks. This paper presents a compiler-agnostic methodology that enables high-level synthesis (HLS) tools to target custom FPGA hardblocks directly from C/C++ code. Architectural hardblocks are exposed as schedulable C-level operators using an RTL blackbox abstraction with explicit latency and initiation-interval contracts, allowing the HLS scheduler to optimize around specialized hardware without manual RTL orchestration. Unlike traditional uses of HLS blackboxes for external IP integration, our approach treats blackboxes as architectural abstractions, enabling scalable composition of C-level operators that target custom FPGA hardblocks without compiler modification. We evaluate the proposed flow using a Tensor Slice-based FPGA architecture with AMD Vitis HLS and the Verilog-to-Routing (VTR) toolchain. Across multiple matrix sizes, designs generated using the proposed C-Blackbox flow achieve lower area-delay product than behavioral HLS baselines while providing substantially higher productivity-adjusted efficiency than handwritten RTL implementations. These results demonstrate that domain-specific FPGA architectures can be made accessible through HLS while maintaining competitive hardware efficiency.
arXiv:2605.26078v3 Announce Type: replace Abstract: Wasserstein policy gradient (WPG) is a policy optimization method for reinforcement learning (RL) that exploits the optimal-transport geometry of action distributions. For the entropy-regularized RL objective, WPG evolves each state-conditional policy by transporting it along the action gradient of the soft Q-function together with a Langevin-type diffusion. Despite its appeal for continuous-control problems, its global convergence properties remain poorly understood. Standard Langevin analyses do not directly apply, because the RL objective depends on the policy through the Bellman recursion rather than through a static convex functional, and the Langevin drift is determined by the soft Q-function, whose regularity must be controlled along the policy iterates. In this paper, we develop a global convergence theory for WPG by exploiting the Bellman structure of entropy-regularized RL. We show that the role usually played by convexity can be replaced by a Bellman-based argument: the soft Bellman residual admits a statewise KL representation with respect to a Gibbs policy; Bellman contraction relates this residual to the global optimality gap; and a Bellman resolvent identity connects value improvement to relative Fisher information. Combined with a uniform log-Sobolev inequality (LSI) for the evolving Gibbs family, these ingredients yield a distributional Polyak--\L{}ojasiewicz condition. We further establish the regularity and uniform bounds needed to control the discretization error, thereby obtaining geometric contraction up to a discretization bias. Conceptually, our analysis shows that although entropy-regularized RL is not convex in the usual flat sense, the Bellman recursion induces a favorable Polyak--Lojasiewicz-type (PL) geometry that supports global convergence of WPG.
arXiv:2606.08388v1 Announce Type: new Abstract: Muon replaces a matrix gradient $G=U\Sigma V^\top$ by its polar factor $UV^\top$. This keeps the singular directions selected by the gradient, but makes the update spectrum flat. We study the optimization bias created by this operation. Under explicit alignment assumptions, we prove that the polar update is the one-step entropy-maximizing choice among bounded updates that use the gradient singular directions and do not adapt to the current weight spectrum. In an underdetermined regression model, we derive exact singular-value dynamics for continuous-time Muon and identify a measurement-dependent condition under which the normalized spectrum moves toward equal nonzero singular values. This geometry also rules out a common low-rank interpretation: at fixed Frobenius norm, Muon's distinguished state has a flat spectrum, whereas nuclear-norm minimization favors spectral concentration. Controlled matrix-sensing experiments separate the effect from simple gradient rescaling, show that norm-matched gradient descent does not reproduce Muon, and recover the predicted flattening trend across broad ablations. In small NanoGPT pretraining, Muon preserves stable rank, has a broad learning-rate plateau, and improves validation loss relative to AdamW; in a matched small-ViT control, the ranking reverses. The resulting picture is regime-dependent: Muon is not universally superior, but its flat-spectrum bias can help when many spectral directions need to remain active.
arXiv:2606.08680v1 Announce Type: new Abstract: Fisheye cameras are widely deployed in autonomous driving perception suites for their low cost and full-coverage field of view (FOV), yet their potential remains underleveraged in 3D object detection. Severe radial distortion challenges most BEV detectors by violating the fundamental assumption of uniform sampling. To bridge this gap, we propose Distortion-Aware PETR (DAPETR), a projection-free detector tailored for mixed pinhole-fisheye camera setups. DAPETR incorporates two key learned-adaptive modules: a unified distortion-aware positional embedding that harmonizes positional encodings for image representations with fisheye geometry, and a bidirectional feature-geometry co-modulation module that mutually adapts image features and 3D positional embeddings. In our experiments on a converted KITTI-360 benchmark, we systematically compare our learned adaptive approach against PETR in polar coordinates (PolarPETR). We find that while both methods improve over the baseline, our learned modules achieve superior performance. Crucially, we uncover a negative interaction when combining both strategies, revealing that learned adaptation and explicit geometric reparameterization can conflict. Our final DAPETR model significantly advances the research and benchmark for fisheye BEV detection, providing critical insights into effective distortion-aware 3D perception design other than image rectification.
arXiv:2606.08394v1 Announce Type: new Abstract: Multimodal language models are typically evaluated through external behavior: selecting the correct image--text match, rejecting unsupported captions, or answering visual queries correctly. However, correct behavior alone does not show that the model's internal decision state remains stable under controlled semantic stress. We study this gap through S$^3$E (Structured Semantic Stress Evaluation), a framework for analyzing behavior-internal decoupling in multimodal language models. S$^3$E uses a positive-anchored A/B forced-choice setup in which an image-supported caption is contrasted against semantic stress candidates under both original and swapped option orders, while hidden states are extracted at the pre-answer decision state. We focus on strict-correct trials, where the model consistently selects the correct caption across both orders. Rather than treating arbitrary hidden-state variation as evidence of instability, we measure whether semantic-conflict candidates induce excess decision-state displacement relative to meaning-preserving controls. Across Qwen3VL, Gemma3, and InternVL3, semantic stress consistently produces positive selected-layer excess displacement over lexical controls despite correct forced-choice behavior, while comparisons against random negatives are model-dependent. We interpret this as a scoped decision-state stress-sensitivity signal rather than evidence of downstream failure or hallucination. Our results suggest that forced-choice correctness alone is not a sufficient certificate of invariant internal decision geometry.
arXiv:2606.08400v1 Announce Type: new Abstract: Graduate-level research reading report assessment creates a substantial labor burden for educators. While large language models (LLMs) hold great potential for automating academic grading, their reliability for this specialized task remains understudied, particularly regarding grading consistency, the lack of which represents a primary obstacle to educational fairness. This paper proposes a human-aligned LLM-assisted grading workflow and presents a case study based on 180 student submissions from a graduate advanced software engineering course. We evaluate two mainstream LLMs, Grok and GPT, in terms of grading consistency and alignment with human scores. We find LLMs exhibit distinct levels of intra-model consistency and significant inter-model grading inconsistencies, while simple ensemble approaches cannot improve alignment with human evaluation. Critically, continuous interaction history drives systematic drift in models' grading standards away from human expert scores. Our findings demonstrate LLMs' potential in reducing grading workload for educators in graduate education, while highlighting that indiscriminate LLM grading may introduce systemic unfairness, suggesting that specific operational practices are required to mitigate such disparities.
arXiv:2605.26108v3 Announce Type: replace Abstract: Recent advances in few-step diffusion distillation have enabled efficient image generation, yet aligning these models with human preferences remains challenging. We propose Reward-Tilted Distribution Matching Distillation (RTDMD), a two-stage framework that unifies distribution matching distillation with reward-guided reinforcement learning for few-step flow generators. We show that minimizing the KL divergence to a reward-tilted teacher distribution naturally decomposes into a distribution matching term and a reward maximization term. In the first stage, we introduce Ambient-Consistent Distribution Matching Distillation (AC-DMD), which performs subinterval-wise distribution matching and augments the fake score objective with a consistency regularizer to help the fake score model track the shifting generator distribution under limited updates. In the second stage, we jointly optimize both terms: for the reward maximization term, we derive a hybrid policy gradient that combines a GRPO-style estimator for the stochastic intermediate transitions with direct reward backpropagation through the deterministic final step, and further introduce step-subset GRPO (SubGRPO) to reduce variance. Experiments on SD3, SD3.5, and FLUX.2 demonstrate that RTDMD establishes new state-of-the-art results across preference, aesthetic, and compositional metrics with only 4 inference steps, outperforming previous few-step text-to-image generation methods. Code and models are available at https://github.com/Harahan/RTDMD.
arXiv:2606.08411v1 Announce Type: new Abstract: Block-wise semi-autoregressive decoding is the standard inference paradigm for diffusion large language models (DLMs), but it imposes a strict dependency between blocks: the next block cannot begin until the current block is fully decoded or its denoising budget is exhausted. We observe that once a block exposes a reliable delimiter boundary or stable semantic prefix, continuation generation need not wait for every residual token to be resolved. We propose AsyncLane, a training-free decoding scheduler that decouples refinement from advancement. AsyncLane forks a generate lane at observed delimiter boundaries into a refine lane and a continuation generate lane: the prefix remains editable, while the continuation advances before prefix refinement finishes. The resulting lane tree records decoding dependencies and output order, while execution proceeds over the active lane set. To make this asynchronous schedule efficient under bidirectional attention, AsyncLane combines shared-prefix lane batching, lookahead draft reuse, cascading termination, and compact cache refresh with refresh-logit reuse, preventing model-call cost from scaling directly with the number of lanes. AsyncLane is a drop-in replacement for block-wise DLM samplers and requires no retraining. Experiments on mathematical reasoning and code generation show that AsyncLane consistently improves throughput while maintaining competitive quality. Across LLaDA and Dream backbones, AsyncLane achieves the highest TPS in all evaluated benchmark-length settings; relative to the fastest competing baseline, it reaches peak speedups of 2.95x on LLaDA and 3.04x on Dream, with especially large gains under longer generation budgets.
arXiv:2606.08413v1 Announce Type: new Abstract: We present a structured analysis of how contemporary clinical AI systems integrate electronic health record (EHR) data and the extent to which they support longitudinal clinical reasoning. Drawing on a curated corpus of clinical natural language processing (NLP) and EHR-integrated systems, we develop a coding framework that captures both technical integration strategies and reasoning-relevant representational features, such as trajectory modeling, cross-encounter synthesis, longitudinal analysis, and absence reasoning. We also elicited the experiences of three physicians in their EHR use, including what strengths and weaknesses they found with their institution's current EHR system(s). Our analysis shows that while many systems incorporate EHR data, they predominantly operate on encounter-level or aggregated representations, with limited support for explicit temporal reasoning across patient histories. Reasoning-relevant structures are inconsistently represented, and evaluation paradigms remain largely focused on predictive performance instead of longitudinal interpretability. We argue that current approaches treat EHR data as a static input rather than a substrate for ongoing clinical reasoning, and we outline a framework for understanding how future systems might more effectively align with the temporal and interpretive structure of clinical practice.
arXiv:2606.08968v1 Announce Type: new Abstract: Surface-level reactor antineutrino experiments usually have substantial cosmic ray induced neutron backgrounds, particularly with shallow overburden. The Array of Lattice for Anti-neutrino Reactor Monitoring (ALARM) is a plastic scintillator based experiment designed for reactor power monitoring. It will be deployed about 44 m from the core of a reactor at the Taishan Nuclear Power Plant. Placed at a depth of 9.6 meters below the surface, cosmic ray induced fast neutrons constitute a significant background, making an effective neutron shielding system essential for the experiment. For the shielding design of ALARM, we tested the shielding performance of three materials water, HDPE, and 40\% boron-doped HDPE (BHDPE) against both fast and thermal neutrons. A thermal neutron detector composed of an EJ426 scintillator setup was first used to measure the shielding efficiency of these materials at various thicknesses using neutrons from an Am-Be source. A 30-cm thickness of BHDPE achieved a shielding efficiency exceeding 95\% for both fast and thermal neutrons. Monte Carlo simulations of the EJ426 setup yielded results consistent with the experimental data. Simulation results for the shielding performance of the full ALARM shielding assembly are also presented.
arXiv:2606.08712v1 Announce Type: new Abstract: Purpose: Spatial transcriptomics (ST) enables gene expression measurements within the tissue context. However, these measurements are often noisy, low-resolution, and sparsely sampled, which limits the recovery of fine spatial structure. Deep neural networks have become powerful tools for expression imputation from histology, but their performance remains constrained by limited sample sizes and a lack of biologically informed augmentation. Most of the existing augmentation strategies for learning are designed for classification tasks rather than regression, which neglect spatial and transcriptomic relationships, leading to biologically implausible interpolations that hinder prediction performance. Approach: To address these limitations, we propose SNR-ST-Mix, a geometry- and expression-aware data augmentation framework designed specifically for ST data. It constrains mixing to a spot's k-nearest spatial neighbors and adaptively weights interpolation coefficients based on expression similarity, generating augmented samples that preserve local biological structure while ensuring spatial smoothness. This dual conditioning yields synthetic examples that expand the effective training manifold, promote generalization, and enhance prediction stability under sample-specific training. Results: Extensive experiments with various tissue types demonstrate that SNR-ST-Mix consistently outperforms conventional augmentation methods without requiring architectural changes or additional computation. Conclusions: SNR-ST-Mix provides an effective and biologically principled augmentation strategy for spatial transcriptomics regression tasks. By explicitly leveraging spatial geometry and transcriptomic similarity, it expands the effective training manifold and improves predictive performance without increasing model complexity.
arXiv:2606.09495v1 Announce Type: new Abstract: Modern object detectors achieve strong performance on standard benchmarks, yet their robustness to contextual variation remains insufficiently understood. Prior evaluations largely rely on aggregate metrics such as AP on uncontrolled distribution shifts, which can obscure how performance degrades under context change. We introduce ContextShift, a controlled benchmark that systematically manipulates object--context relationships while preserving object appearance. Built on COCO 2017, it isolates context as an independent variable through geometric transformations and synthetic and natural background substitutions, including a continuous compatibility axis based on normalized pointwise mutual information (NPMI). Across diverse detector architectures, we observe a consistent degradation pattern: false negatives increase by up to 227% and prediction volume decreases by up to 44%, while false positives remain stable or decline. This suppression behavior is not captured by aggregate metrics such as AP, which can mask substantial recall loss and changes in prediction dynamics. Further analysis suggests that degradation is driven less by reduced confidence than by a reduced formation of valid detection candidates. Moreover, performance along the statistical compatibility axis is non-monotonic, peaking at intermediate NPMI and degrading toward both extremes, indicating that statistical co-occurrence does not correlate linearly with effective visual context. Finally, we show that context-aware augmentation improves robustness: every augmented variant outperforms the dataset-only baseline on both original and manipulated test images, partially recovering performance lost to prediction-suppression failures by exposing models to object--context decoupling during training.
arXiv:2606.08421v1 Announce Type: new Abstract: Multi-contrast brain MRI provide complementary soft-tissue characteristics that aid in the screening and diagnosis of diseases. However, limited scanning time, image corruption and various imaging protocols often result in incomplete multi-contrast images. While current approaches excel in image synthesis, they often struggle to synthesize critical tumor regions and exploit contextual information in multi-contrast brain MRI effectively. To address this issue, we propose a synthesis-centric, segmentation-assisted closed-loop framework with retrieval augmentation synthesis. Our method overall takes a generative adversarial architecture, which aims to synthesize missing contrasts from any combination of available ones with a single model. To explicitly capture tumor semantics and focus synthesis on tumor regions, we add an auxiliary segmentation branch that predicts tumor masks and feeds them back as semantic conditioning in synthesis branch, thereby learning tumor-aware representations in the model and improving synthesis fidelity. Furthermore, we propose a dual-bank retrieval augmentation strategy. It dynamically queries two external knowledge bases, namely a tumor masks memory bank for crucial tumor context and cross-image contrast feature memory bank for global style information, to augment synthesis. Verified on two public multi-contrast magnetic resonance brain datasets: BraTs2020 and UCSF-BMSR, the proposed method is effective in handling medical brain images synthesis tasks and shows superior performance compared to previous methods. Code is available at:https://github.com/iBizzard/SSCF.git
arXiv:2606.08426v1 Announce Type: new Abstract: We present CritLens, a visual analytics system that helps users build personalized multi-criteria decision models from review text. In everyday decisions -- choosing equipment, hotels, or restaurants -- evaluation criteria are either preset by platforms or generated by LLMs, leaving users unable to discover, adjust, or verify them against the underlying evidence. This is problematic because many preferences are latent: they surface only upon encountering specific reviews, and any fixed framework risks overlooking low-frequency but decisive details. CritLens addresses this gap by using LLMs to transform reviews into an initial AHP decision model, then supporting iterative, human-in-the-loop refinement. Through coverage gap detection in the embedding space, users discover criteria missed by the initial model; through interactive weight adjustment under AHP consistency constraints, they express personal priorities; and through a multi-level scorecard and exportable decision report, they trace every ranking back to the original review text. Two case studies, an eight-participant user study, and a quantitative consistency-repair experiment demonstrate the system's effectiveness.
arXiv:2606.08431v1 Announce Type: new Abstract: This paper studies neural ordinary differential equations (neural ODEs) from a control-theoretic perspective using controllability and observability concepts. The neural ODE is represented in a control-affine form to facilitate analysis using tools from nonlinear and linear time-varying (LTV) systems. Controllability is examined through trajectory linearization, where the LTV controllability Gramian provides a local, first-order measure of input influence along a nominal trajectory. Observability is analyzed through output linearization, where the LTV observability Gramian characterizes the local ability to reconstruct system states from output measurements. Koopman-based lifting is considered to extend the analysis to a higher-dimensional representation, and its limitations under multiple equilibria and basin-dependent behavior are discussed. The proposed framework is illustrated on a series RLC circuit. The learned neural ODE reproduces system trajectories and generalizes to unseen initial conditions. The computed Gramians are numerically full rank along the tested trajectories, indicating local controllability and observability of the linearized dynamics.