arXiv:2606.12403v1 Announce Type: new Abstract: Vision-Language-Action (VLA) models inherit semantic grounding from large-scale pretraining and perform competently across in-distribution manipulation tasks. This grounding, however, is built on static image-text pairs, whereas manipulation is a continuous, contact-rich process whose dynamics this pretraining cannot capture. We present World Pilot, a VLA framework that augments the policy with priors from a World-Action Model (WAM), routed into the decision chain through two complementary pathways. Latent Steering conditions the perception layer on a scene-evolution latent, and Action Steering supplies an anticipated trajectory as a motion prior to the action generator. Together the two priors equip the VLA with an anticipated view of the scene and a trajectory-level motion hint alongside its semantic conditioning, and the scene-evolution prior remains effective even when supplied by a video-pretrained world model that has not been action-post-trained. World Pilot attains a state-of-the-art Total success rate of 84.7% on the LIBERO-Plus zero-shot OOD benchmark and the highest success rate on every real-robot setting across four manipulation tasks, with the largest margins under shifts in viewpoint, geometry, deformable state, and pose. Project Website: https://world-pilot.github.io/
Science Journals
arXiv:2605.25692v1 Announce Type: cross Abstract: Homomorphic quantum error correction aims to protect quantum data against both unauthorized access and environmental noise during server-based processing. We investigate the algebraic compatibility between quantum homomorphic encryption and quantum error correction, determining precise conditions under which encrypted encoded states remain inside the relevant code space during storage and computation. Our work establishes a necessary and sufficient criterion for an $[[n,1,d]]$ stabilizer code to remain compatible with the restricted transversal block-Pauli masking $U_{\rm enc}(a,b)=(X^aZ^b)^{\otimes n}$, stated explicitly for $[[n,1,d]]$ codes and extending directly to code-space preservation for $[[n,k,d]]$ codes. We verify this condition for standard examples (bit-flip and Shor codes, with the phase-flip repetition code following analogously), derive a practical criterion for Calderbank-Shor-Steane codes, and extend the analysis to three-dimensional color codes. A critical challenge emerges for non-Clifford gate implementation: the Shor code lacks a naive transversal $T$-gate implementation of the desired logical operation on encrypted encoded data. We present two routes around this obstruction. First, suitable triorthogonal codes admit transversal $T$-type logical implementations, up to Clifford corrections. Second, logical-gate masking gives code-space compatibility for arbitrary stabilizer codes, provided that suitable unitary representatives of the required logical gates are available. These results separate code-space compatibility from a full cryptographic security proof and provide explicit criteria for combining error correction with homomorphic processing in cloud quantum computing.
arXiv:2606.11737v1 Announce Type: cross Abstract: Close-in exoplanets exhibit a wide range of orbital architectures and physical properties shaped by both formation conditions and migration processes. Although population-synthesis models predict distinct planetary populations, establishing a quantitative connection between observed exoplanets and synthetic populations remains challenging. We investigate the intrinsic organisation of close-in exoplanets using physically motivated dynamical parameters and connect the resulting populations to pebble-accretion formation pathways. A two-stage Gaussian mixture model (GMM) is applied to an observed sample of close-in exoplanets, performing unsupervised probabilistic clustering in a feature space dominated by dynamical descriptors of planet-star interactions. The resulting clusters are mapped onto a pebble-accretion synthetic population within a statistically motivated three-dimensional parameter space. Formation-related quantities, including gas availability, gas fraction, and ice-rock mass ratio, are then used to interpret the mapped populations. We identify statistically supported sub-populations without imposing predefined classification boundaries, including very-massive gas giants, hot giants, warm-Jupiter-dominated systems, and lower-mass giants. The mapped synthetic populations reveal systematic differences in formation timing, gas accretion, and solid growth histories. In particular, very-massive gas giants are preferentially associated with earlier formation epochs than hot-giant and warm-Jupiter-dominated populations. These results demonstrate that physically motivated machine-learning approaches can provide a statistically robust framework for linking observed exoplanet populations to theoretical planet formation pathways.
arXiv:2606.11773v1 Announce Type: cross Abstract: Optimistic Gradient Descent Ascent (OGDA) and Optimistic Multiplicative-Weights Update (OMWU) are two very popular algorithms to solve convex/concave saddle-point problems, where OMWU is the non-Euclidean, entropic version of OGDA. It is known since the '80s that the last iterate of OGDA asymptotically converges to a saddle point in smooth problems. On the other hand, it is unknown if OMWU has the same property. In this paper, I show that OMWU converges asymptotically for smooth convex-concave saddle-point problems, with a small enough constant learning rate. The result does not require uniqueness, strict complementarity, an error bound, or initialization near a solution. The main new ingredient is a boundary argument showing that every cluster point satisfies the inactive-coordinate KKT inequalities. The boundary argument was discovered with assistance from ChatGPT and is documented in the appendix.
arXiv:2606.12173v1 Announce Type: cross Abstract: Randomness amplification, the task of extracting uniform private bits from biased seeds that may be partly known by a malicious third party, is of central importance in cryptography. The highest security in this task is provided by a class of quantum protocols known as device-independent, which however are challenging to integrate into scalable devices. Semi-device-independent (SDI) protocols are a promising alternative that guarantees security under few natural assumptions, such as bounds on the amount of energy used by the devices. Here, we provide the first demonstration of SDI randomness amplification on an integrated silicon photonic chip, achieving a throughput rate of 20 Mbps suitable for practical applications. This rate is achieved through a novel technique for SDI entropy certification, which delivers strictly tighter von Neumann entropy bounds compared to existing methods and remains valid even if the preparation and measurement devices share quantum correlations. Overall, the methods developed in this work enable the integration of SDI technology into portable telecom devices, opening up a new generation of quantum cryptographic hardware.
arXiv:2606.12409v1 Announce Type: cross Abstract: Fractional quantum Hall states are a cornerstone of topological physics, hosting fractionally charged quasiparticles with exotic statistics that promise to enable topologically protected quantum information processing. Among these, the Pfaffian state introduced by Moore and Read implements a p-wave pairing structure that supports excitations with non-Abelian exchange statistics. Despite extensive study in electronic systems, direct access to its pairing structure has remained limited. Here we realize a three-particle bosonic Pfaffian state of ultracold $^{87}\mathrm{Rb}$ atoms in an optical lattice subject to a Floquet-engineered synthetic magnetic field. Using a Bayesian-optimized adiabatic protocol, we prepare a state exhibiting Pfaffian pairing correlations. Site-resolved measurements of multi-point density correlations reveal a pronounced suppression of short-range three-body coincidences, reflecting the underlying pairing structure. We further probe the state's transport response through Hall drift measurements. Our results establish a bottom-up approach to engineering non-Abelian topological order and lay the groundwork for future explorations of anyonic braiding in synthetic matter.
arXiv:2412.09023v3 Announce Type: replace Abstract: Channel and spatial attention mechanisms introduced in earlier work enhance the representational capabilities of deep convolutional neural networks (CNNs) but often increase parameter and computational costs. While recent approaches focus solely on efficient feature context modeling for channel attention, we aim to model both channel and spatial attention comprehensively with minimal parameters and reduced computation. Leveraging the principles of relational modeling in graphs, we introduce a constant-parameter module, \textit{STEAM: Squeeze and Transform Enhanced Attention Module}, which integrates channel and spatial attention to enhance the representation power of CNNs. To our knowledge, we are the first to propose a graph-based approach for modeling both channel and spatial attention, utilizing concepts from multi-head graph transformers. Additionally, we introduce \textit{Output Guided Pooling} (OGP), which efficiently captures spatial context to further enhance spatial attention. We extensively evaluate STEAM for large-scale image classification, object detection and instance segmentation on standard benchmark datasets. STEAM achieves a \(2\%\) increase in accuracy over the standard ResNet-50 model with only a meager increase in GFLOPs. Furthermore, STEAM outperforms the leading modules, ECA and GCT, in terms of accuracy while achieving a threefold reduction in GFLOPs. The code will be made available upon acceptance.
arXiv:2506.02568v2 Announce Type: replace Abstract: Large Language Models (LLMs) have demonstrated substantial efficacy in advancing graph-structured data analysis. Prevailing LLM-based graph methods excel in adapting LLMs to text-rich graphs, wherein node attributes are text descriptions. However, their applications to multimodal graphs--where nodes are associated with diverse attribute types, such as texts and images--remain underexplored, despite their ubiquity in real-world scenarios. To bridge the gap, we introduce the Multimodal Large Language and Graph Assistant (MLaGA), an innovative model that adeptly extends LLM capabilities to facilitate reasoning over complex graph structures and multimodal attributes. We first design a structure-aware multimodal encoder to align textual and visual attributes within a unified space through a joint graph pre-training objective. Subsequently, we implement a multimodal instruction-tuning approach to seamlessly integrate multimodal features and graph structures into the LLM through lightweight projectors. Extensive experiments across multiple datasets demonstrate the effectiveness of MLaGA compared to leading baseline methods, achieving superior performance in diverse graph learning tasks under both supervised and transfer learning scenarios.
arXiv:2508.09459v3 Announce Type: replace Abstract: Visual manipulation localization (VML) aims to identify tampered regions in images and videos, a task that has become increasingly challenging with the rise of advanced editing tools. Existing methods face two central issues. The first is resolution diversity. Resizing or padding can distort subtle forensic cues and introduce unnecessary computational cost. The second is the difficulty of extending spatial models for images to spatio-temporal inputs in videos, which often results in maintaining separate architectures for the two data types. To address these challenges, we propose RelayFormer, a unified framework that adapts to varying resolutions and naturally handles both static and temporal visual data. RelayFormer partitions inputs into fixed-size sub-images and introduces Global Local Relay (GLR) tokens that propagate structured context through a relay-based attention mechanism. This design enables efficient exchange of global cues, such as semantic or temporal consistency, while preserving fine-grained manipulation artifacts. Unlike prior approaches that depend on uniform resizing or sparse attention, RelayFormer scales to variable resolutions and video sequences with minimal overhead. Experiments across diverse benchmarks demonstrate superior performance and strong efficiency, combining resolution adaptivity without interpolation or excessive padding, unified processing for images and videos, and a favorable balance between accuracy and computational cost. Code is available at~\href{https://github.com/WenOOI/RelayFormer}{https://github.com/WenOOI/RelayFormer}.
arXiv:2509.11548v2 Announce Type: replace Abstract: Graphical user interface (GUI) grounding is a fundamental task for building GUI agents. However, general vision-language models (VLMs) struggle with this task due to a lack of specific optimization. We identify a key gap in this paper: while VLMs exhibit significant latent grounding potential, as demonstrated by their performance measured by Pointing Game, they underperform when tasked with outputting explicit coordinates. To address this discrepancy and bypass the high data and annotation costs of current fine-tuning approaches, we propose three zero-shot auxiliary reasoning methods. By providing explicit spatial cues such as axes, grids and labeled intersections as part of the input image, these methods enable VLMs to better articulate their implicit spatial understanding capabilities. We evaluate these methods on four GUI grounding benchmarks across seven open-source and proprietary VLMs. Experimental results show substantial gains from auxiliary reasoning. Mark-Grid Scaffold boosts Gemini-3.1-Pro from 11.72\% under direct inference to 95.20\% on ScreenSpot-v2, achieves state-of-the-art performance on ScreenSpot, and approaches the strongest fine-tuned methods on ScreenSpot-v2 and UI-I2E-Bench. Our code is available at https://github.com/liweim/AuxiliaryReasoning.
arXiv:2510.23508v3 Announce Type: replace Abstract: Existing real-world datasets for multimodal fact-checking have multiple limitations: they contain few instances, cover on only one or two languages, focus only on one task, or rely on external news article sets for sourcing true claims. To address these shortcomings, we introduce M4FC, a new real-world dataset comprising 4,982 images paired with 6,980 claims. The images, verified by professional fact-checkers from 22 organizations, represent a diverse range of cultural and geographic contexts. Each claim is available in one or two out of ten languages. M4FC spans six multimodal fact-checking tasks: visual claim extraction, claimant intent prediction, fake image detection, image contextualization, location verification, and verdict prediction. We provide baseline results for all tasks and analyze how combining intermediate tasks affects verdict prediction performance. We make our dataset and code publicly available.
arXiv:2510.24515v2 Announce Type: replace Abstract: The Team Orienteering Problem (TOP) generalizes many real-world multi-agent scheduling and routing tasks that occur in autonomous mobility, aerial logistics, and surveillance applications. While many flavors of the TOP exist for planning in multi-agent systems, they assume that all the agents cooperate toward a single objective; therefore, they do not extend to settings when they compete in reward-scarce environments. We propose Stochastic Prize-Collecting Orienteering Games (SPCOG) as an extension of the TOP to plan in the presence of self-interested agents operating on a graph, under energy constraints and stochastic transitions. A theoretical discussion on complete and star graphs establishes that there is a unique pure Nash equilibrium in SPCOGs that coincides with the optimal routing solution of an equivalent TOP under rank-based conflict resolution. We propose the concept of Ordinal Rank (OR) as a concise representation of an agents' global rank and its location within a topological, well-defined neighborhood. Empirical evaluations conducted on real-world, road-network graphs under both dynamic and stationary prize distributions show that in parameter-sharing settings, the policies that leverage local information can outperform those policies leverage global information when the former is conditioned on the OR rather than the global rank, indicating that the OR acts as a strong inductive bias in multi-agent games on graphs. The OR-conditioned policies also generalize much better to games with large number of agents compared to global-rank conditioned policies. Finally, we also propose we propose Fictitious Ordinal Response Learning (FORL) as an entropy-regulated algorithm to obtain convergent policies in independent-learning settings in prize-collecting games on graphs.
arXiv:2606.11719v1 Announce Type: new Abstract: Spatial reasoning remains a persistent challenge for multimodal large language models (MLLMs). Existing approaches largely rely on large-scale, statically curated datasets, where all training samples are treated uniformly regardless of the model's evolving capabilities. This static paradigm is inherently data-inefficient: training capacity is often spent on samples that are either trivial or overly difficult for the model at its current stage. To address this limitation, we propose Ouroboros-Spatial, a self-evolving training framework in which the model plays dual roles as a proposer and a solver. In each iteration, a frozen proposer generates spatial question-answer (QA) pairs from 3D scene metadata and raw video frames, together with executable code for deriving reliable ground truth. A learnable solver is then fine-tuned on the accepted samples, and its per-sample prediction confidence is used as a difficulty signal. This signal is fed back to the proposer in the next iteration, guiding it to generate questions better matched to the solver's current capabilities. Through this closed-loop design, the training distribution co-evolves with model ability, reducing redundant trivial examples while filtering out ambiguous or uninformative samples with limited learning value. Across six spatial reasoning benchmarks, Ouroboros-Spatial substantially improves Qwen3-VL-4B and Qwen3-VL-8B while using an order of magnitude fewer training examples than recent large-scale curated datasets. On VSI-Bench, it yields absolute gains of 9.9 and 6.8 points for the 4B and 8B models, respectively, enabling both to outperform a wide range of strong open-source and proprietary baselines.
arXiv:2601.23278v2 Announce Type: replace Abstract: Diffusion Large Language Models (DLLMs) offer a compelling alternative to Auto-Regressive models, but their deployment is constrained by high decoding cost. In this work, we identify a key inefficiency in DLLM decoding: while computation is parallelized over token blocks, only a small subset of tokens is decodable at each diffusion step, causing most compute to be wasted on non-decodable tokens. We further observe a strong correlation between attention-derived token importance and token-wise decoding probability. Based on this insight, we propose FOCUS, an inference system designed for DLLMs. By dynamically focusing computation on decodable tokens and evicting non-decodable ones on-the-fly, FOCUS increases the effective batch size, alleviating compute limitations and enabling scalable throughput. Empirical evaluations demonstrate that FOCUS achieves up to 3.52$\times$ throughput improvement over the production-grade engine LMDeploy in large-batch settings, while preserving or improving generation quality across multiple benchmarks.
arXiv:2602.06547v4 Announce Type: replace Abstract: LLM-based coding agents increasingly rely on third-party extensions called skills, which bundle natural language instructions and helper scripts that execute with full user privileges. Community registries have emerged to distribute these skills, but the security implications remain unstudied due to the absence of labeled threat data. This paper presents a systematic security analysis of 98,380 skills collected from two major registries. Through a combination of static pattern matching and dynamic behavioral verification, we identify 157 skills exhibiting confirmed malicious behavior, encompassing 632 distinct vulnerabilities across 13 attack techniques. Our analysis reveals that these threats are deliberate rather than accidental: each malicious skill contains an average of 4.03 vulnerabilities spanning multiple attack phases. We identify two dominant attack strategies with statistically significant negative correlation -- credential theft via remote code execution, and agent manipulation through adversarial instructions embedded in documentation. Over half of all confirmed cases originate from a single threat actor employing templated brand impersonation at scale. We further observe that attack sophistication correlates with concealment investment, with advanced skills universally employing undocumented capabilities while also exploiting platform-native trust mechanisms. Following responsible disclosure, registry maintainers removed all 157 (100%) of the reported skills. Our dataset and detection pipeline are publicly available to facilitate future research on securing LLM agent ecosystems.
arXiv:2602.06827v3 Announce Type: replace Abstract: In this paper, we introduce DynaRetarget, a complete pipeline for retargeting human motions to humanoid control policies. The core component of DynaRetarget is a novel Sampling-Based Trajectory Optimization (SBTO) framework that refines imperfect kinematic trajectories into dynamically feasible motions. SBTO incrementally advances the optimization horizon, enabling optimization over the entire trajectory for long-horizon tasks. We validate DynaRetarget by successfully retargeting hundreds of humanoid-object demonstrations and achieving higher success rates than the state of the art. The framework also generalizes across varying object properties, such as mass, size, and geometry, using the same tracking objective. This ability to robustly retarget diverse demonstrations opens the door to generating large-scale synthetic datasets of humanoid loco-manipulation trajectories, addressing a major bottleneck in real-world data collection.
arXiv:2602.06868v2 Announce Type: replace Abstract: Zero-order optimization has recently received significant attention for designing optimal trajectories and policies for robotic systems. However, most existing methods (e.g., MPPI, CEM, and CMA-ES) are local in nature, as they rely on gradient estimation. In this paper, we introduce consensus-based optimization (CBO) to robotics, which is guaranteed to converge to a global optimum under mild assumptions. We provide theoretical analysis and illustrative examples that give intuition into the fundamental differences between CBO and existing methods. To demonstrate the scalability of CBO for robotics problems, we consider three challenging trajectory optimization scenarios: (1) a long-horizon problem for a simple system, (2) a dynamic balance problem for a highly underactuated system, and (3) a high-dimensional problem with only a terminal cost. Our results show that CBO is able to achieve lower costs with respect to existing methods on all three challenging settings. This opens a new framework to study global trajectory optimization in robotics.
arXiv:2603.13854v2 Announce Type: replace Abstract: We introduce power term polynomial algebra, a representation language for Boolean formulae designed to bridge conjunctive normal form (CNF) and algebraic normal form (ANF). The language is motivated by the tiling mismatch between these representations: direct CNF<->ANF conversion may cause exponential blowup unless formulas are decomposed into smaller fragments, typically through auxiliary variables and side constraints. In contrast, our framework addresses this mismatch within the representation itself, compactly encoding structured families of monomials while representing CNF clauses directly, thereby avoiding auxiliary variables and constraints at the abstraction level. We formalize the language through power terms and power term polynomials, define their semantics, and show that they admit algebraic operations corresponding to Boolean polynomial addition and multiplication. We prove several key properties of the language: disjunctive clauses admit compact canonical representations; power terms support local shortening and expansion rewrite rules; and products of atomic terms can be systematically rewritten within the language. Together, these results yield a symbolic calculus that enables direct manipulation of formulas without expanding them into ordinary ANF. The resulting framework provides a new intermediate representation and rewriting calculus that bridges clause-based and algebraic reasoning and suggests new directions for structure-aware CNF<->ANF conversion and hybrid reasoning methods.
arXiv:2603.21639v2 Announce Type: replace Abstract: Accurately estimating human mobility in peripheral regional economies presents a fundamental measurement challenge: physical ground-truth sensors are sparse, behavioral intent signals are heterogeneous, and environmental friction introduces systematic bias into demand inference. We introduce the Distributed Human Data Engine (DHDE), a multi-modal sensor fusion architecture that addresses this challenge by integrating physical instrumentation (Edge-AI cameras), digital intent signals (route search impression metrics), behavioral records (90,350 spending records, 97,719 standardized survey responses), and meteorological data across four geographically distributed nodes in Fukui, Japan. The primary measurement-science contribution is the design, deployment, and cross-node validation of the DHDE as a sparse-sensor compensation instrument: a heterogeneous sensor fusion architecture that anchors non-stationary digital intent signals to concurrent physical ground-truth counts, correcting for systematic bias introduced by meteorological planning friction. The instrument is implemented as an ensemble inference pipeline (Random Forest and Ordinary Least Squares with Newey-West robust inference), calibrated across 397 daily observations and validated by chronological holdout replication across four geographically distinct node types. The primary OLS specification achieved an in-sample explanatory power of R2 = 0.810 and a chronological out-of-sample predictive performance of R2 = 0.683. Results identify an Under-Vibrancy Paradox where macro-regional visitor satisfaction correlates positively with crowd density (Spearman rank correlation rs = +0.150, p = 0.002). We estimate an annual proxy gap of 865,917 intent-implied visits, corresponding to JPY 11.96 billion (USD 72.6 million) in foregone revenue.
arXiv:2604.07833v4 Announce Type: replace Abstract: Embodied Agents are evolving from passive reasoning systems into active executors that interact with tools, robots, and physical environments. Once an agent gains execution authority, the central challenge shifts from how to make it act to how to keep its actions governable at runtime. Existing approaches embed safety, recovery, and decision constraints inside the agent loop, making execution control difficult to standardize, audit, and adapt across environments. We propose a runtime governance framework for policy-constrained execution that separates agent cognition from execution oversight. Governance is externalized into a dedicated runtime layer performing policy checking, capability admission, execution monitoring, rollback, and human override. We formalize the control boundary among a persistent Embodied Agent, modular Capability Packages, and the governance layer, and define a policy-constrained execution pipeline evaluated under controlled simulation. Over 1000 randomized trials, the framework achieves 96.2%+/-2.7% interception of unauthorized actions, reduces unsafe continuation from 100% to 22.2%+/-3.1% under runtime drift, and attains 90.7%+/-3.0% recovery success with full policy compliance. Comparison with five baselines, including AutoRT-style constitution filtering and RoboGuard-style two-stage guardrails, shows that pre-execution filtering is equally effective across governance-aware methods, while only the proposed framework provides continuous runtime detection (RVDR = 61.3% vs. 0%) and structured recovery (all p<0.001). A sensitivity sweep across the full detection range confirms a genuine detection-continuation trade-off. This work argues future embodied systems should be designed for governable execution.
arXiv:2604.10242v4 Announce Type: replace Abstract: Despite recent progress in text-prompt-based medical image segmentation, existing LISA-like MLLM-based methods typically generate masks regardless of whether the target specified in the query is present, leading to hallucinated segmentation. In this work, we propose MedVeriSeg, a training-free query verification framework that enables LISA-like medical segmentation models to reject false segmentation queries. MedVeriSeg first quantifies the response quality between the [SEG] token and image features through a Similarity Response Quality Scoring Module. To further improve robustness, it employs a Lightweight Routed Multi-Agent Verification Module, which fuses quantitative score evidence with qualitative agent evidence to comprehensively verify the validity of the query. To support systematic evaluation, we construct MedVeriSeg-Bench, a benchmark designed for query verification in medical image segmentation. Experimental results demonstrate that MedVeriSeg effectively identifies false segmentation queries and reduces hallucinated segmentation, while maintaining a high acceptance rate for valid queries, thereby largely preserving the segmentation utility of LISA-like medical segmentation models.
arXiv:2604.24662v2 Announce Type: replace Abstract: Identifying the dynamical state variables of a system from high-dimensional observations is a central problem across physical sciences. The challenge is that the state variables are not directly observable and must be inferred from raw high-dimensional data without supervision. Here we introduce DySIB (Dynamical Symmetric Information Bottleneck) as a method to learn low-dimensional representations of time-series data by maximizing predictive mutual information between past and future observation windows while penalizing representation complexity. This objective operates entirely in latent space and avoids reconstruction of the observations. We apply DySIB to an experimental video dataset of a physical pendulum, where the underlying state space is known. The method, with hyperparameters of the learning architecture set self-consistently by the data, recovers a two-dimensional representation that matches the dimensionality, topology, and geometry of the pendulum phase space, with the learned coordinates aligning smoothly with the canonical angle and angular velocity. These results demonstrate, on a well-characterized experimental system, that predictive information in latent space can be used to recover interpretable dynamical coordinates directly from high-dimensional data.
arXiv:2604.25701v2 Announce Type: replace Abstract: The RNA world hypothesis suggests a pathway of how life emerged on early earth. It assumes that life started with RNA based systems, capable of storing, transmitting and replicating information, envisioning that monomers and short RNA oligomers interact to form longer strands, eventually becoming catalytically active ribozymes. Key reactions in RNA pools are hybridization, dehybridization, templated ligation, and cleavage. Those reactions depend on many environmental parameters and the wide range of possible configurations among interacting strands. In order to scan such high dimensional parameter spaces, efficient descriptions are needed. Motif rate equations project complex strand reactor dynamics onto sequence motif space. Here we present a Bayesian inference framework to infer their parameters from ligation count data produced by strand reactor simulations. This provides a framework to match the simpler motif rate equations to more complex simulations. Additionally, it is a step towards inferring reaction rate constants directly from experimental data, including rigorous uncertainty estimation. This could be an essential procedure to connect theory and experiment, and deepen our understanding of the essential features necessary for life to emerge.
arXiv:2605.00321v2 Announce Type: replace Abstract: Vision-Language-Action (VLA) policies often fail under distribution shift, suggesting that decisions may depend on spurious visual correlations rather than task-relevant causes. We formulate visual-action attribution as an interventional estimation problem. Accordingly, we introduce the Interventional Significance Score (ISS), an interventional masking procedure for estimating the causal influence of visual regions on action predictions, and the Nuisance Mass Ratio (NMR), a scalar measure of attribution to task-irrelevant features. We analyze the statistical properties of ISS and show that it admits unbiased estimation, and we characterize conditions under which action prediction error provides a valid proxy for causal influence. Experiments across diverse manipulation tasks indicate that NMR predicts generalization behavior and that ISS yields more faithful explanations than existing interpretability methods. These results suggest that interventional attribution provides a simple diagnostic approach for identifying causal misalignment in embodied policies.
arXiv:2605.00545v2 Announce Type: replace Abstract: Inferring cellular trajectories from destructive snapshots is complicated by the challenges of stochasticity and non-conservative mass dynamics such as cell proliferation and apoptosis. Existing unbalanced Optimal Transport (OT) methods treat mass as a continuous fluid, performing inference at the population level. However, this macroscopic view often fails to capture the discrete, jump-like nature of birth-death events at single-cell resolution, which is essential for understanding lineage branching and fate decisions. We present Unbalanced Schr\"odinger Bridge (USB), a simulation-free framework for learning underlying dynamics that effectively integrates both stochastic and unbalanced effects which also models the discrete, jump-like birth-death dynamics at single-cell resolution. Theoretically, USB provides a tractable solution to the Branching Schr\"odinger Bridge (BSB) problem, offering a rigorous microscopic interpretation where individual cells undergo both Brownian motion and discrete birth-death jumps. Technically, the method implements an efficient solver by introducing a simulation-free training objective that effectively scales to high-dimensional omics data. Empirically, we demonstrate on both simulated and real-world datasets that USB not only achieves trajectory reconstruction performance better than or comparable to deterministic baselines but also uniquely enables realistic discrete simulation of birth-death dynamics at single-cell resolution.