JAMA Senior Editor Derek C. Angus, MD, MPH, spoke with Dost Öngür, MD, PhD, JAMA Psychiatry Editor, and Jeremy Veenstra-VanderWeele, MD, a professor of developmental neuropsychiatry at Columbia University, about autism spectrum disorder for the Healthy Dialogue podcast.
Science Journals
To the Editor A recent study that used a propensity score and 1:3 matching provided valuable insight into the potential effect of glucagon-like peptide 1 receptor agonists (GLP-1RAs) during pregnancy. Nevertheless, several limitations warrant careful consideration.
To the Editor A recent study examining gestational weight gain and pregnancy outcomes after discontinuation of GLP-1RAs before conception provided timely evidence in a rapidly evolving therapeutic landscape. However, several methodological and clinical aspects warrant clarification to avoid premature conclusions regarding safety.
This retrospective cohort study examines treatment failure and adverse events in standard-dose amoxicillin compared with amoxicillin-clavulanate in adults with acute sinusitis.
Ray Lyman Wilbur, M.D., Stanford University, Calif.
To the Editor We write in response to a recent Viewpoint, which contained false statements and misunderstandings about restorative reproductive medicine (RRM) that need to be corrected.
In Reply We appreciate the Letter from Dr Minjeur and colleagues regarding our Viewpoint, as well as the opportunity for clarifications.
Cleaning out her bedside stand unused back-rub gift certificates.
This Perspective discusses the importance of the US Food and Drug Administration’s draft guidance on the use of bayesian methods in clinical trials because it underscores its commitment to modernizing clinical research.
Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.
In Reply We thank Dr Liu and colleagues for their thoughtful engagement with our study and for highlighting important methodological considerations. We welcome the opportunity to clarify these points.
In the Research Letter titled “Trends in Vitamin K Administration Among Infants,” published in the December 8, 2025, issue of JAMA, there were errors in the reported total number of newborns included in the study. It should have been noted that 15 354 of 526 341 newborns in 2017 and 37 187 of 717 402 newborns in 2024 did not receive intramuscular vitamin K. This article was corrected online.
This descriptive analysis uses a subset of data from the Malarial Impact on Neurobehavioral Development (MIND) cohort study to assess whether severe malaria in Ugandan children is associated with long-term cognitive impairment or decreased academic achievement.
This review discusses the epidemiology, clinical presentation, diagnosis, surgical management, histopathologic and molecular characteristics, and adjuvant treatment for endometrial cancer.
In Reply We appreciate that a one-size-fits-all approach to breast cancer screening is increasingly anachronistic, given the heterogeneity of breast cancer and the imbalanced distribution of risk factors across the population. The WISDOM results demonstrated that a risk-based strategy can stratify population risk, facilitating personalized screening and prevention strategies while preserving safety.
This JAMA Clinical Guidelines Synopsis summarizes the American College of Gastroenterology’s 2024 guideline on treatment of Helicobacter pylori infection.
This Medical News article discusses the emergence of a new, research-focused independent autism group in the US following recent changes to the federal Interagency Autism Coordinating Committee.
In this narrative medicine essay, a palliative care physician discusses the impact that the death of her brother had on her time as an attending physician working in the emergency department.
This Viewpoint explores the entry of AI into clinical care, the role of the US Food and Drug Administration, and the associated legal, public health, and medical implications.
Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.
The US Food and Drug Administration (FDA) approved insulin icodec-abae, marketed as Awiqli, making it the first once-weekly basal insulin treatment option for adults with type 2 diabetes.
The US Food and Drug Administration (FDA) approved the oral glucagon-like peptide-1 (GLP-1) receptor agonist orforglipron, marketed as Foundayo, for daily use in people with overweight or obesity. Unlike other oral GLP-1 drugs, orforglipron can be taken any time of day without food or water restrictions.
The burden of hypertension has increased globally over the past 2 decades, particularly in low- and middle-income countries, according to a study published in the Journal of the American College of Cardiology.
Promotion of prescription drugs by social media influencers was consistently associated with misinformation, research found.