Hälsa & medicin

A major review of clinical trials shows therapist-supported internet-based cognitive behaviour therapy produces equivalent outcomes to face-to-face sessions for psychiatric and somatic disorders. The finding has significant implications for healthcare systems seeking to expand mental health access while managing costs and capacity constraints.EN

A new analysis examines whether removing the entire pancreas—instead of the standard partial removal—can reduce life-threatening infections after surgery in high-risk patients. The finding could reshape treatment decisions for pancreatic cancer and other conditions, affecting hospital protocols and surgical outcomes across the sector.EN

A new analysis examines whether indirect calorimetry—a test measuring how many calories patients burn—should become standard care or remain reserved for specific cases. The answer could reshape nutrition protocols in hospitals and care facilities, affecting both patient outcomes and operational costs.EN

A comprehensive review finds no clear consensus on whether negative-pressure wound therapy prevents complications after abdominal surgery, leaving hospitals without definitive guidance on adoption. The finding matters because surgical wound infections drive up costs and readmissions — but hospitals cannot yet determine if this preventive technology justifies its expense.EN

A major review of Enhanced Recovery After Surgery (ERAS) protocols spanning 20+ years reveals their continued impact on patient outcomes, yet researchers are signaling the need for next-generation improvements. For hospitals and surgical centers, the findings suggest current ERAS frameworks have matured—and that competitive advantage now lies in what comes next.EN

A major respiratory medicine journal has published a response to disputed research findings, settling disagreement among clinicians about clinical practices. The clarification matters for hospitals and healthcare providers who rely on peer-reviewed guidance to shape treatment protocols and patient outcomes.EN

A new study in Hepatology addresses a high-stakes clinical debate: whether living donor liver transplants are appropriate for patients with primary sclerosing cholangitis, a progressive bile duct disease. The findings could shape transplant protocols and patient outcomes at major medical centers.EN

A major clinical trial found that daratumumab combined with lenalidomide and dexamethasone improved outcomes for multiple myeloma patients at initial diagnosis. The results could reshape treatment protocols and expand the addressable market for these therapies across oncology practices and hospital systems.EN

Researchers have identified how bladder cancer tumors turn on telomerase—a cellular mechanism that allows cancer cells to divide indefinitely. The discovery could enable doctors to better predict which patients need aggressive treatment and potentially develop new drugs targeting this vulnerability.EN

A major review of studies shows that combining cognitive and motor exercises significantly improves dual-task performance in Parkinson's disease patients—the ability to do two things at once, like walking while talking. The finding has implications for treatment protocols and could reduce fall risk and disability in a growing patient population.EN

Hepatologists are moving toward population-level approaches to liver disease management rather than treating patients one at a time. The shift reflects a growing recognition that liver health outcomes depend on broader public health infrastructure, clinical coordination, and preventive strategies—a change with significant implications for healthcare policy and resource allocation.EN

Researchers have mapped how senescent cells—the worn-out cells that accumulate with age—disrupt immune function and drive age-related diseases. The findings could unlock treatments for conditions from cancer to neurodegeneration, representing a significant opportunity for pharmaceutical development and preventive healthcare strategies.EN

A new editorial highlights how analyzing cerebrospinal fluid and blood biomarkers could accelerate neurodegenerative disease research and drug trials. For pharmaceutical companies and healthcare systems, this approach promises to identify disease progression earlier and validate new treatments more efficiently than traditional methods.EN

Researchers are making progress using cell sheets—layers of living cells—to rebuild heart tissue damaged by heart attacks and disease. The approach could eventually offer patients an alternative to transplants and significantly expand the market for regenerative medicine therapies.EN

A comprehensive analysis of sepsis care protocols finds that conservative fluid strategies perform as well as aggressive volume replacement. The finding could reshape clinical guidelines and reduce complications in millions of patients, with significant implications for hospital protocols and intensive care standards.EN

Researchers have synthesized decades of data on labor progression patterns, offering clearer benchmarks for clinicians. The findings could reshape delivery protocols and reduce unnecessary interventions—affecting hospital practices, liability exposure, and maternal outcomes across healthcare systems.EN

Researchers in Sweden are launching a trial to evaluate whether distance-based exercise delivery can improve outcomes for breast, prostate, and colorectal cancer patients. The results could shape how healthcare systems design survivorship programs and whether insurers cover remote rehabilitation services.EN

A new editorial challenges organizations to stop making claims about flexible work's benefits without solid evidence. As companies invest heavily in remote and hybrid arrangements, researchers warn that sustainability claims often lack the data to back them up, creating risk for businesses and workers alike.EN

A major analysis confirms that regular physical activity significantly lowers the risk of heart disease, cancer, and premature death. For insurers, employers, and public health planners, the findings quantify just how much activity matters—and suggest where prevention efforts should focus to reduce healthcare costs.EN

Researchers analyzed decades of workplace mental health programs and found that targeted interventions work better than company-wide initiatives. The findings matter because employers waste billions on ineffective wellness programs—this guide shows where to focus investment for measurable results.EN

A comprehensive review of prospective studies reveals connections between circulating sex hormone levels and gastrointestinal cancer development. The findings could reshape screening strategies and prevention approaches for patients at elevated hormonal risk, with implications for pharmaceutical companies developing cancer prevention therapies.EN

Researchers are mapping connections between DNA repair mechanisms and the endocrine system, suggesting hormonal dysfunction may play a role in how cells respond to genetic damage. Understanding this relationship could reshape treatment approaches for cancer, metabolic disease, and aging-related conditions affecting millions globally.EN

A new systematic review identifies major safety concerns with checkpoint inhibitors and targeted therapies used to treat melanoma, but reveals a troubling gap in how these toxicities are tracked and reported. For pharmaceutical companies, health systems, and regulators, the finding underscores an urgent need for standardized safety monitoring to help clinicians manage these powerful drugs more effectively.EN

A new study finds that infants born prematurely or with low birth weight face significantly higher risk of developing nonalcoholic fatty liver disease later in life. The finding suggests that early-life conditions may have lasting metabolic consequences, potentially expanding the window for preventive health interventions and affecting how clinicians assess disease risk.EN

Researchers have identified how citrullination—a protein modification process—drives inflammation at the skin barrier. The finding could open new treatment pathways for chronic skin conditions affecting millions and create commercial opportunities for companies developing targeted therapies.EN