Scientists pinpoint how bladder cancer cells activate immortality mechanism

Researchers have identified how bladder cancer tumors turn on telomerase—a cellular mechanism that allows cancer cells to divide indefinitely. The discovery could enable doctors to better predict which patients need aggressive treatment and potentially develop new drugs targeting this vulnerability.

Originaltitel: <i>TERT</i> promoter mutations and methylation for telomerase activation in urothelial carcinomas: New mechanistic insights and clinical significance