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Scientists find psoriasis fingerprint in DNA switches controlling key skin genes

Researchers identified distinctive DNA methylation patterns in psoriatic skin that disrupt microRNA genes linked to the Wnt pathway, a crucial regulator of cell growth and inflammation. The discovery could unlock new diagnostic markers and drug targets for a condition affecting 2-3% of the population and generating billions in annual treatment spending.

Originaltitel: Differential DNA Methylation of MicroRNA- Encoding Genes in Psoriatic Epidermis Highlights the Wnt Pathway

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