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Hälsa & medicin 4.4

Nearly half of young adults with skin disease skip prescribed drugs

A study of over 2,900 young adults in Sweden found that 45% of those diagnosed with atopic dermatitis never filled prescriptions for treatment—even basic moisturizers. The findings suggest significant gaps in how sex, wealth, and disease severity influence medication access, with implications for pharmaceutical companies, healthcare systems, and policymakers trying to close treatment disparities.

Originaltitel: Drug utilization among young adults with atopic dermatitis: Influence of sex, socio-economic status and disease severity

Abstrakt

<p>Background</p><p>Atopic dermatitis (AD) affects individuals of all ages, and the first-line treatment are emollients and topical corticosteroids. There is insufficient knowledge about factors possibly affecting the drug utilization of young adults with AD.</p><p>Objectives</p><p>To describe the drug utilization of young adults with AD in relation to sex, socio-economic status and disease severity.</p><p>Methods</p><p>A cross-sectional study based on the 24-year follow-up from the population-based BAMSE (Children, Allergy, Milieu, Stockholm, Epidemiology Survey) birth cohort linked with dispensing data from the National Drug Register (<em>n</em> = 2912). Self-reported AD and socio-economic status were defined from questionnaire data and disease severity was determined through the clinical examination and Patient-Oriented Eczema Measure questionnaire.</p><p>Results</p><p>The prevalence of AD in young adults was 17.7% (<em>n</em> = 516) and 45.5% of them were dispensed at least one drug for the treatment of AD during the study period (January 2016 to June 2019). Topical corticosteroids (TCS) were the most common drugs (32.9%) followed by emollients (21.7%). A larger proportion of men were dispensed TCS than women (39.0% vs. 29.1%: <em>p</em>-value = 0.020). A larger proportion of young adults with moderate-to-severe AD were dispensed TCS than those with mild AD (52.6% vs. 35.3%: <em>p</em>-value = 0.026). No one was dispensed the recommended amount of emollients and less than five individuals were dispensed the recommended amount of TCS for mild disease. Male sex (adj.OR 1.54, 95% CI 1.06–2.34) and moderate-to-severe AD (adj.OR 2.62, 95% CI 1.59–4.31) were associated with dispensation of TCS.</p><p>Conclusions</p><p>A large proportion of young adults with AD was undertreated or untreated. Sex and disease severity did affect the dispensing patterns of investigated drugs.</p>

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