New technique bridges gap between brain scans and direct recordings
Neuroscientists have developed a method to simultaneously capture brain activity using both non-invasive and invasive sensors, offering unprecedented insight into how the brain works. The advance could accelerate drug development, improve epilepsy treatment, and help companies and regulators understand neurological conditions more effectively.
Originaltitel: Simultaneous invasive and non-invasive recordings in humans: a novel Rosetta stone for deciphering brain activity
<p>Simultaneous noninvasive and invasive electrophysiological recordings provide a unique opportunity to achieve a comprehensive understanding of human brain activity, much like a Rosetta stone for human neuroscience. In this review we focus on the increasingly-used powerful combination of intracranial electroencephalography (iEEG) with scalp electroencephalography (EEG) or magnetoencephalography (MEG). We first provide practical insight on how to achieve these technically challenging recordings. We then provide examples from clinical research on how simultaneous recordings are advancing our understanding of epilepsy. This is followed by the illustration of how human neuroscience and methodological advances could benefit from these simultaneous recordings. We conclude with a call for open data sharing and collaboration, while ensuring neuroethical approaches and argue that only with a true collaborative approach the promises of simultaneous recordings will be fulfilled.</p>