Lab test for Lyme disease can backfire when antibodies are too high

Researchers have confirmed a paradoxical problem in Borrelia serology tests: patients with the strongest immune response to Lyme disease can get false negative results. The finding could reshape how clinicians interpret tests and diagnose infections, potentially affecting treatment decisions for millions tested annually.

Originaltitel: When more is less: follow-up on the hook effect in Borrelia serology