Scientists identify genetic switch that could prevent heart scarring

Researchers have pinpointed a gene that drives cardiac fibrosis—the dangerous scarring of heart tissue after injury or high blood pressure. Blocking this gene in animal models reversed the damage, suggesting a potential new drug target for the millions of heart failure patients worldwide and a significant market opportunity for pharmaceutical developers.

Originaltitel: Inhibition of long noncoding RNA Gm41724 alleviates pressure overload-induced cardiac fibrosis by regulating lamina-associated polypeptide 2α