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Hälsa & medicin 5.1

Scientists discover new drug candidates targeting hidden JAK2 protein domain

Researchers have identified small molecule compounds that bind to a previously overlooked part of the JAK2 protein, opening a potential new avenue for treating blood cancers and inflammatory diseases. The finding could enable drug developers to design therapies that work differently from existing JAK inhibitors, potentially overcoming resistance and side effects that limit current treatments.

Originaltitel: Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain

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