Boosting a Key Parkinson's Protein Fails to Protect Brain Cells in New Study

A mouse study finds that increasing GDNF, a protein long considered protective for dopamine neurons, provides no benefit in Parkinson's disease models. The finding challenges a leading therapeutic strategy and suggests developers need to rethink how to deliver or deploy the protein to be effective.

Originaltitel: Increased Physiological GDNF Levels Have No Effect on Dopamine Neuron Protection and Restoration in a Proteasome Inhibition Mouse Model of Parkinson?s Disease