Brain's stress-response gene linked to psychiatric disease and aging

Researchers have identified a gene called FKBP5 as a convergence point between psychiatric illness and aging, with expression changes concentrated in a specific brain layer. The finding could reshape how pharmaceutical companies develop treatments targeting stress-related disorders and age-related neurodegeneration—two of the fastest-growing cost drivers in healthcare.

Originaltitel: Associations of psychiatric disease and ageing with <i>FKBP5</i> expression converge on superficial layer neurons of the neocortex