Scientists identify RNA switch that triggers heart scarring disease

Researchers have pinpointed a molecule called THBS1-AS1 that activates the cellular process leading to cardiac fibrosis, a life-threatening condition where heart tissue hardens. The discovery, published in JCI Insight, could unlock new drug targets for treating heart failure and other fibrotic diseases affecting millions globally.

Originaltitel: The long noncoding RNA THBS1-AS1 promotes cardiac fibroblast activation in cardiac fibrosis by regulating TGFBR1