Alzheimer's researchers target protein to restore brain rhythm disruption

Scientists have identified galectin-3 as a driver of neural dysfunction in Alzheimer's disease, specifically how it disrupts the brain's electrical synchronization critical for memory and cognition. The finding opens a new therapeutic avenue for a protein that could be drugged, potentially slowing cognitive decline before irreversible brain damage occurs.

Originaltitel: Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer's disease