New genetic test could identify Alzheimer's risk years before symptoms appear

Researchers have developed a polygenic risk score that uses common genetic variants to predict who will develop Alzheimer's disease, potentially decades in advance. The advance could reshape clinical trial recruitment, enable earlier interventions, and create a new market for preventive diagnostics—but raises questions about how employers and insurers might use genetic risk data.

Originaltitel: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores (vol 12, 3417, 2021)