Rogue immune cells fuel colon cancer spread, opening new treatment target

Researchers identified a specific subset of pericyte cells that actively promote colorectal cancer metastasis by remodeling tissue surrounding blood vessels. The discovery could lead to drugs that block these cells, potentially preventing cancer spread without harming the tumor itself—a significant shift in how oncologists approach metastatic disease.

Originaltitel: Novel TCF21<SUP>high</SUP> pericyte subpopulation promotes colorectal cancer metastasis by remodelling perivascular matrix