Silica Dust Triggers Unexpected DNA Damage Pathway in Lung Cells

Researchers discovered that crystalline silica particles activate a previously unknown mechanism that damages lung cell DNA, potentially explaining why silica exposure causes cancer and respiratory disease. The finding could reshape how regulators assess workplace silica risks and open new targets for protecting workers in mining, construction, and manufacturing.

Originaltitel: ATX-LPA-Dependent Nuclear Translocation of Endonuclease G in Respiratory Epithelial Cells: A New Mode Action for DNA Damage Induced by Crystalline Silica Particles