Metal ions could be key to stopping Alzheimer's protein clumping

Nickel ions influence how amyloid beta proteins fold and clump together, a finding that could reshape drug development strategies for Alzheimer's disease. Understanding these metal-protein interactions opens new avenues for therapies targeting the root cause of neurodegeneration rather than just its symptoms.

Originaltitel: Residue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides