Scientists map how coronavirus variants grip human cells at molecular level

Researchers used single-molecule imaging to reveal how different COVID-19 spike variants bind to human ACE2 receptors with varying strength, a finding that could guide vaccine design and help predict which variants pose the greatest infection risk. Understanding these molecular mechanics may enable faster responses to future coronavirus threats.

Originaltitel: Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level(Dec, 10.1038/s41467-022-35641-3,2022)