Immune cells sense acid levels to trigger allergies, opening new drug targets

Researchers identified how immune cells detect pH changes in their environment and use that signal to drive allergic responses. The discovery of the GPR65 receptor's role could enable pharmaceutical companies to develop the first drugs that block allergies at this fundamental level, potentially disrupting a market currently dominated by symptom-managing antihistamines.

Originaltitel: pH sensing shapes immune cell function: The role of GPR65 and its implications for allergic disease