Study maps immune cell genes that drive heart disease progression

Researchers have identified distinct genetic patterns in immune cells at different stages of atherosclerosis using mouse models, revealing how gene expression shifts as plaque builds up in arteries. The findings could guide development of targeted therapies that intervene at specific disease stages, potentially opening new markets for precision cardiovascular treatments.

Originaltitel: A comparative gene expression matrix in Apoe-deficient mice identifies unique and atherosclerotic disease stage-specific gene regulation patterns in monocytes and macrophages