Scientists reveal how a hidden genetic switch drives leukemia and controls DNA repair

Researchers have discovered that a molecular modification called m6A controls how cells produce a critical protein that affects both cancer development and genomic stability. The finding could open new therapeutic angles for treating blood cancers by targeting this previously underappreciated control mechanism.

Originaltitel: m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis