Skipping surgery for rectal cancer shows promise, but outcomes vary

A major international study finds that some rectal cancer patients can safely avoid surgery after chemotherapy if their tumors disappear completely—but those with partial responses face higher risks. The findings could reshape treatment protocols and reduce unnecessary procedures, though doctors remain cautious about expanding the approach without clearer predictive markers.

Originaltitel: Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database (IWWD)