HIV drug resistance tied to patient's viral load at treatment start

A new study identifies which HIV patients are most likely to fail on modern integrase inhibitor drugs—those with high viral loads and low CD4 counts at the start of therapy. The findings could help clinicians predict treatment failure early and adjust care strategies, potentially reducing costly drug switches and hospitalizations.

Originaltitel: Plasma Human Immunodeficiency Virus 1 RNA and CD4<SUP>+</SUP> T-Cell Counts are Determinants of Virological Nonsuppression Outcomes With Initial Integrase Inhibitor-Based Regimens: A Prospective RESPOND Cohort Study