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Life Sciences 6.4

Scientists discover hidden protein-folding power in cell quality-control system

Researchers have identified a new molecular chaperone function within the BRICHOS domain, a protein structure previously known mainly for managing misfolded proteins. The finding could reshape how biotech companies design therapeutics for neurodegenerative diseases and protein-folding disorders that cost billions annually in healthcare spending.

Originaltitel: A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain

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