New pathway for controlling inflammation could reshape drug development

Researchers have identified how blocking a key enzyme redirects the body's inflammatory response through alternative biological pathways. The finding could inform the design of next-generation anti-inflammatory drugs and help companies understand why some existing treatments have unexpected effects on immune function.

Originaltitel: Microsomal prostaglandin E synthase-1 inhibition promotes shunting in arachidonic acid metabolism during inflammatory responses in vitro