Protein switch controls how immune cells stay ready for gut infections

Scientists identified a protein called Bcl11b that acts as a master control for intestinal immune cells, keeping them flexible and combat-ready rather than locked into a single mode. The finding could help vaccine designers and biotech firms develop better defenses against food-borne pathogens and chronic gut diseases.

Originaltitel: Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8+T cells