Life Sciences
6.6
Immune cells find workaround when key defense protein is missing
Researchers discovered that B cells can compensate for a missing immune regulator by boosting an alternative signaling pathway. The finding suggests the immune system has built-in redundancies that could inform drug development for autoimmune diseases and cancer immunotherapy.
Originaltitel: Enhanced B Cell Receptor Signaling Partially Compensates for Impaired Toll-like Receptor 4 Responses in LPS-Stimulated IκBNS-Deficient B Cells