Gene deletion predicts outcomes in childhood leukemia subtypes

Researchers have identified IKZF1 gene deletions as a prognostic marker in two major forms of childhood acute lymphoblastic leukemia. The finding could help clinicians better stratify patients for treatment intensity, potentially improving survival rates and reducing overtreatment in lower-risk cases.

Originaltitel: The Prognostic Effect of<i> IKZF1</i> Deletions in <i>ETV6::RUNX1</i> and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia