Study maps immune cell dysfunction in childhood inflammatory bowel disease

Researchers have created a detailed cellular map of immune dysfunction in children with colitis, identifying which immune cells go awry in the disease. The findings could guide development of more targeted treatments and help predict which children will respond to existing therapies, potentially reducing trial-and-error prescribing in pediatric gastroenterology.

Originaltitel: The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis