Genetic markers predict sarcoidosis blood cell loss, opening diagnostic path

Researchers identified genetic variants in HLA-DRB1 that predict low lymphocyte counts in sarcoidosis patients, a common inflammatory disease. The finding could improve early diagnosis and patient stratification without requiring invasive lung biopsies, potentially reducing diagnostic delays and healthcare costs for a condition affecting hundreds of thousands globally.

Originaltitel: Peripheral blood lymphopenia in sarcoidosis associates with <i>HLA-DRB1</i> alleles but not with lung immune cells and organ involvement