Researchers find drug combination approach to overcome neuroblastoma resistance

Scientists identified how pairing an mPGES-1 inhibitor with other drugs can break through chemotherapy resistance in neuroblastoma, a deadly childhood cancer. The findings, based on advanced lab screening, could reshape treatment strategies and open new commercial pathways for combination therapies in this notoriously difficult-to-treat disease.

Originaltitel: High-content screening of drug combinations of an mPGES-1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance