Alzheimer's hits men and women differently, study finds

A new analysis of brain cells reveals that Alzheimer's disease progresses through distinct biological pathways in women versus men—one involving cellular dysfunction, the other immune activation. The finding could reshape how drugmakers design treatments and how clinicians stratify patients, potentially improving efficacy across both sexes.

Originaltitel: Single-Nucleus Transcriptomics Analysis Identifies Sex-Dichotomous Pathological Axes in Alzheimer’s Disease: Female Homeostatic Failure versus Male Neuroimmune Activation