New method maps hidden genetic switches in brain tumors after surgery

Researchers have developed a computational tool that reveals how gene regulation and protein production interact in pituitary tumors that return after surgery. The finding could help doctors predict which patients face recurrence and identify new treatment targets, potentially improving outcomes for a common brain tumor with limited therapeutic options.

Originaltitel: Hypernetwork modelling reveals epigenome-proteome interactions in post-surgical progression of non-functioning pituitary adenomas